Basic Information
ID: ALA827973
Type: Functional
Description: Inhibitory concentration against Gamma-secretase in whole cell inhibition assay using SH-SY5Y cells
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA827973
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 493.09 | 4.22 | 4.22 |
| 491.12 | 5.37 | 5.37 |
| 511.11 | 3.71 | 3.71 |
| 506.14 | 4.13 | 4.13 |
| 495.11 | 4.74 | 4.74 |
| 568.21 | 5.71 | 5.71 |
| 474.05 | 4.78 | 4.78 |
| 497.08 | 3.32 | 3.32 |
| 497.08 | 3.58 | 3.58 |
| 383.56 | 4.46 | 4.46 |
| 367.92 | 3.87 | 3.87 |
| 385.91 | 4.01 | 4.01 |
| 447.56 | 3.81 | 3.81 |
| 511.04 | 5.56 | 5.56 |
| 384.50 | 3.12 | 3.12 |
| 494.08 | 3.91 | 3.91 |
| 395.45 | 4.18 | 4.18 |
| 447.56 | 3.81 | 3.81 |
| 345.44 | 3.30 | 3.30 |
| 440.61 | 4.68 | 4.68 |
| 508.11 | 4.30 | 4.30 |
| 279.40 | 2.12 | 2.12 |
| 293.43 | 2.51 | 2.51 |
| 385.91 | 4.01 | 4.01 |
| 327.45 | 3.16 | 3.16 |
| 345.44 | 3.30 | 3.30 |
| 488.03 | 4.52 | 4.52 |
| 402.37 | 4.53 | 4.53 |
| 511.04 | 5.56 | 5.56 |
| 454.64 | 4.92 | 4.92 |
| 510.08 | 3.14 | 3.14 |
| 307.46 | 2.90 | 2.90 |
| 345.44 | 3.30 | 3.30 |
| 321.49 | 3.29 | 3.29 |
| 474.63 | 4.73 | 4.73 |
| 402.37 | 4.53 | 4.53 |
| 342.46 | 2.74 | 2.74 |
| 345.44 | 3.30 | 3.30 |
| 511.04 | 5.56 | 5.56 |
| 414.53 | 2.74 | 2.74 |
| 496.10 | 4.15 | 4.15 |
| 341.48 | 3.47 | 3.47 |
| 397.95 | 3.88 | 3.88 |
| 341.48 | 3.47 | 3.47 |
| 333.48 | 3.22 | 3.22 |
| 383.92 | 3.58 | 3.58 |
| 355.50 | 3.72 | 3.72 |
| 446.57 | 4.41 | 4.41 |
| 476.60 | 4.91 | 4.91 |
| 523.12 | 3.06 | 3.06 |
| 402.37 | 4.53 | 4.53 |
| 372.45 | 3.07 | 3.07 |
| 361.89 | 3.81 | 3.81 |
| 517.07 | 5.62 | 5.62 |
| 447.56 | 3.81 | 3.81 |
| 530.12 | 4.60 | 4.60 |
| 495.11 | 4.74 | 4.74 |
| 509.14 | 5.13 | 5.13 |
| 585.20 | 4.63 | 4.63 |
| 544.14 | 4.94 | 4.94 |