Basic Information
ID: ALA830912
Type: Functional
Description: Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cells
Organism: Homo sapiens
Cell type: SKBr3
Activity Charts
Bioactivity
Activity Types for Assay ALA830912
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 433.87 | 3.23 | 3.23 |
| 401.47 | 2.45 | 2.45 |
| 399.43 | 2.58 | 2.58 |
| 381.44 | 2.44 | 2.44 |
| 343.84 | 3.63 | 3.63 |
| 351.44 | 3.18 | 3.18 |
| 378.29 | 4.28 | 4.28 |
| 451.91 | 3.79 | 3.79 |
| 428.35 | 4.30 | 4.30 |
| 412.73 | 4.93 | 4.93 |
| 455.92 | 2.72 | 2.72 |
| 423.93 | 4.04 | 4.04 |
| 339.42 | 2.98 | 2.98 |
| 393.39 | 3.87 | 3.87 |
| 419.51 | 3.01 | 3.01 |
| 361.43 | 2.05 | 2.05 |
| 421.48 | 2.07 | 2.07 |
| 433.92 | 3.65 | 3.65 |
| 339.42 | 2.98 | 2.98 |
| 378.29 | 4.28 | 4.28 |
| 369.45 | 2.99 | 2.99 |
| 345.43 | 2.38 | 2.38 |
| 405.48 | 2.40 | 2.40 |
| 339.42 | 2.98 | 2.98 |
| 437.50 | 3.15 | 3.15 |
| 441.92 | 4.18 | 4.18 |
| 378.29 | 4.28 | 4.28 |
| 451.51 | 1.69 | 1.69 |
| 337.45 | 3.59 | 3.59 |
| 346.63 | 4.00 | 4.00 |
| 312.18 | 3.39 | 3.39 |
| 359.46 | 2.99 | 2.99 |
| 389.48 | 3.39 | 3.39 |
| 371.42 | 1.66 | 1.66 |
| 374.47 | 3.76 | 3.76 |
| 369.45 | 2.99 | 2.99 |
| 337.45 | 3.59 | 3.59 |
| 471.94 | 3.80 | 3.80 |
| 465.32 | 3.59 | 3.59 |
| 432.30 | 3.46 | 3.46 |
| 391.45 | 1.67 | 1.67 |
| 414.49 | 2.58 | 2.58 |
| 411.84 | 4.65 | 4.65 |
| 488.40 | 4.32 | 4.32 |
| 399.48 | 3.00 | 3.00 |
| 355.42 | 2.00 | 2.00 |
| 339.42 | 2.47 | 2.47 |
| 343.84 | 3.63 | 3.63 |
| 345.74 | 3.71 | 3.71 |
| 375.45 | 2.01 | 2.01 |
| 417.47 | 3.14 | 3.14 |
| 431.47 | 1.68 | 1.68 |
| 525.37 | 3.60 | 3.60 |
| 337.45 | 3.59 | 3.59 |
| 373.87 | 3.64 | 3.64 |
| 418.32 | 3.74 | 3.74 |
| 329.43 | 3.37 | 3.37 |
| 435.51 | 2.03 | 2.03 |