ID: ALA830957
Type: Binding
Description: Inhibition of rat liver dihydrofolate reductase
Organism: Rattus norvegicus
Bioactivity
Activity Types for Assay ALA830957
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
329.40 | 1.88 | 1.88 |
359.43 | 1.88 | 1.88 |
337.21 | 3.07 | 3.07 |
318.38 | 2.91 | 2.91 |
321.41 | 3.57 | 3.57 |
321.41 | 3.57 | 3.57 |
314.35 | 1.75 | 1.75 |
340.24 | 3.72 | 3.72 |
331.40 | 2.43 | 2.43 |
304.36 | 2.89 | 2.89 |
323.19 | 3.04 | 3.04 |
340.39 | 2.13 | 2.13 |
330.39 | 3.26 | 3.26 |
319.37 | 3.18 | 3.18 |
347.38 | 3.79 | 3.79 |
314.78 | 2.76 | 2.76 |
372.64 | 3.98 | 3.98 |
370.41 | 2.14 | 2.14 |
322.39 | 3.83 | 3.83 |
331.38 | 3.67 | 3.67 |
340.39 | 2.13 | 2.13 |
368.44 | 2.91 | 2.91 |
354.41 | 2.15 | 2.15 |
340.39 | 2.13 | 2.13 |
382.47 | 2.93 | 2.93 |
354.41 | 2.15 | 2.15 |
354.41 | 2.15 | 2.15 |
340.39 | 2.13 | 2.13 |
305.34 | 3.15 | 3.15 |
305.34 | 3.15 | 3.15 |
356.39 | 1.83 | 1.83 |
322.39 | 3.83 | 3.83 |
354.41 | 2.15 | 2.15 |
356.39 | 1.83 | 1.83 |
294.36 | 1.87 | 1.87 |
280.33 | 1.84 | 1.84 |
358.40 | 3.59 | 3.59 |
280.33 | 1.83 | 1.83 |
316.37 | 2.95 | 2.95 |
346.39 | 2.96 | 2.96 |
340.39 | 1.84 | 1.84 |
370.41 | 1.85 | 1.85 |
266.31 | 1.80 | 1.80 |
326.36 | 1.82 | 1.82 |
326.36 | 1.82 | 1.82 |
340.39 | 1.84 | 1.84 |
326.36 | 1.82 | 1.82 |
356.39 | 1.83 | 1.83 |
370.41 | 2.39 | 2.39 |
356.39 | 1.83 | 1.83 |
356.39 | 1.83 | 1.83 |
370.41 | 1.85 | 1.85 |
408.46 | 2.16 | 2.16 |
360.42 | 3.27 | 3.27 |
412.49 | 2.94 | 2.94 |
398.47 | 2.55 | 2.55 |
384.44 | 2.16 | 2.16 |
340.39 | 1.84 | 1.84 |
370.41 | 1.85 | 1.85 |
326.36 | 1.82 | 1.82 |
369.64 | 3.76 | 3.76 |
316.37 | 2.95 | 2.95 |
300.75 | 2.45 | 2.45 |
280.33 | 1.83 | 1.83 |
300.75 | 2.45 | 2.45 |
349.23 | 3.13 | 3.13 |
335.20 | 3.11 | 3.11 |
266.31 | 1.80 | 1.80 |
310.36 | 1.83 | 1.83 |
283.36 | 2.48 | 2.48 |
326.36 | 1.82 | 1.82 |
349.23 | 3.13 | 3.13 |
296.33 | 1.81 | 1.81 |
349.23 | 3.13 | 3.13 |
310.36 | 1.83 | 1.83 |
335.20 | 3.11 | 3.11 |
340.39 | 1.84 | 1.84 |
356.39 | 1.83 | 1.83 |
349.23 | 3.13 | 3.13 |
326.36 | 1.82 | 1.82 |
340.39 | 1.84 | 1.84 |
335.20 | 3.11 | 3.11 |
335.20 | 3.11 | 3.11 |
310.36 | 1.83 | 1.83 |
296.33 | 1.81 | 1.81 |
296.33 | 1.81 | 1.81 |
314.78 | 2.48 | 2.48 |
330.40 | 2.98 | 2.98 |
316.37 | 2.95 | 2.95 |
330.39 | 2.98 | 2.98 |
333.42 | 3.63 | 3.63 |
333.42 | 3.63 | 3.63 |
369.64 | 3.76 | 3.76 |
383.67 | 3.79 | 3.79 |
394.39 | 1.47 | 1.47 |
386.46 | 1.70 | 1.70 |
314.35 | 1.75 | 1.75 |
284.32 | 1.74 | 1.74 |
324.39 | 2.14 | 2.14 |
383.67 | 4.07 | 4.07 |
328.81 | 2.79 | 2.79 |
373.26 | 2.90 | 2.90 |
314.78 | 2.76 | 2.76 |
310.36 | 2.12 | 2.12 |
310.36 | 2.12 | 2.12 |
363.25 | 3.44 | 3.44 |
359.23 | 2.87 | 2.87 |
314.78 | 2.76 | 2.76 |
349.23 | 3.42 | 3.42 |
355.40 | 2.43 | 2.43 |
355.40 | 2.43 | 2.43 |
355.40 | 2.43 | 2.43 |
369.43 | 2.46 | 2.46 |
339.40 | 2.45 | 2.45 |
325.37 | 2.42 | 2.42 |
325.37 | 2.42 | 2.42 |
325.37 | 2.42 | 2.42 |
265.32 | 2.41 | 2.41 |
398.42 | 1.69 | 1.69 |
339.40 | 2.45 | 2.45 |
339.40 | 2.45 | 2.45 |
377.24 | 2.97 | 2.97 |
411.68 | 3.62 | 3.62 |
397.48 | 1.91 | 1.91 |
333.44 | 3.04 | 3.04 |
319.41 | 3.01 | 3.01 |
295.39 | 1.81 | 1.81 |
338.24 | 3.16 | 3.16 |
357.46 | 2.66 | 2.66 |
338.24 | 3.16 | 3.16 |
317.82 | 2.54 | 2.54 |
352.27 | 3.19 | 3.19 |
338.24 | 3.16 | 3.16 |
371.49 | 2.68 | 2.68 |
348.25 | 2.62 | 2.62 |
357.46 | 2.29 | 2.29 |
343.43 | 1.90 | 1.90 |
373.46 | 1.91 | 1.91 |
252.28 | 1.93 | 1.93 |
342.36 | 1.96 | 1.96 |
312.33 | 1.95 | 1.95 |
282.31 | 1.94 | 1.94 |
329.39 | 2.36 | 2.36 |
331.36 | 1.03 | 1.03 |
299.36 | 2.35 | 2.35 |
286.73 | 2.59 | 2.59 |
312.33 | 1.95 | 1.95 |
299.36 | 2.35 | 2.35 |
282.31 | 1.94 | 1.94 |
370.41 | 1.85 | 1.85 |
295.35 | 1.98 | 1.98 |
325.37 | 1.99 | 1.99 |
355.40 | 2.00 | 2.00 |
323.36 | 2.38 | 2.38 |
293.33 | 2.37 | 2.37 |
384.44 | 2.24 | 2.24 |
384.40 | 1.38 | 1.38 |
359.43 | 1.88 | 1.88 |
366.43 | 2.08 | 2.08 |
380.45 | 2.07 | 2.07 |
334.38 | 2.51 | 2.51 |
329.41 | 3.58 | 3.58 |
420.48 | 2.42 | 2.42 |
369.43 | 2.46 | 2.46 |
416.53 | 3.64 | 3.64 |
401.47 | 3.29 | 3.29 |
303.80 | 2.51 | 2.51 |
315.38 | 3.56 | 3.56 |
415.54 | 2.32 | 2.32 |
380.41 | 2.21 | 2.21 |
294.36 | 2.13 | 2.13 |
391.44 | 2.61 | 2.61 |