Basic Information
ID: ALA832453
Type: Binding
Description: Concentration required for 50% inhibition of tubulin polymerization
Format: BAO_0000357
Target: Tubulin beta-1 chain(ALA1915)
Document: ALA1141176
Concentration required for 50% inhibition of tubulin polymerization: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA832453
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 316.35 | 3.60 | 3.60 |
| 358.39 | 3.71 | 3.71 |
| 344.36 | 3.32 | 3.32 |
| 325.41 | 4.06 | 4.06 |
| 316.35 | 3.60 | 3.60 |
| 300.35 | 3.89 | 3.89 |
| 298.38 | 4.45 | 4.45 |
| 330.34 | 3.02 | 3.02 |
| 332.35 | 3.11 | 3.11 |
| 320.34 | 3.01 | 3.01 |
| 306.31 | 3.22 | 3.22 |
| 305.33 | 3.17 | 3.17 |
| 394.42 | 2.03 | 2.03 |
| 334.37 | 2.79 | 2.79 |
| 320.34 | 3.01 | 3.01 |
| 362.38 | 2.88 | 2.88 |
| 314.38 | 4.28 | 4.28 |
| 268.36 | 4.50 | 4.50 |
| 256.32 | 4.62 | 4.62 |
| 298.38 | 4.50 | 4.50 |
| 343.38 | 3.20 | 3.20 |
| 378.37 | 4.29 | 4.29 |
| 346.35 | 3.76 | 3.76 |
| 254.33 | 4.19 | 4.19 |
| 280.24 | 3.99 | 3.99 |
| 360.41 | 3.49 | 3.49 |
| 376.38 | 3.73 | 3.73 |
| 304.32 | 3.73 | 3.73 |
| 282.24 | 4.42 | 4.42 |
| 346.35 | 3.76 | 3.76 |
| 252.36 | 4.79 | 4.79 |
| 394.37 | 3.87 | 3.87 |
| 344.36 | 3.32 | 3.32 |
| 330.38 | 3.99 | 3.99 |
| 358.43 | 4.77 | 4.77 |
| 226.28 | 3.57 | 3.57 |
| 270.35 | 4.93 | 4.93 |
| 360.43 | 5.20 | 5.20 |
| 360.38 | 4.15 | 4.15 |
| 387.39 | 3.92 | 3.92 |
| 364.34 | 3.90 | 3.90 |
| 364.34 | 3.90 | 3.90 |
| 346.34 | 2.73 | 2.73 |
| 360.41 | 3.56 | 3.56 |
| 374.39 | 3.30 | 3.30 |
| 330.38 | 3.99 | 3.99 |
| 344.41 | 4.38 | 4.38 |