Basic Information
ID: ALA834174
Type: Binding
Description: Inhibitory concentration at 500 nM against aggrecanase from porcine chondrocytes using [35S]-sulfate (5 mCi/ml) as radioligand and adding IL-1alpha (5 ng/ml) incubated for 10h
Format: BAO_0000019
Organism: Sus scrofa
Target: ADAMTS4(ALA2318)
Document: ALA1139577
Inhibitory concentration at 500 nM against aggrecanase from porcine chondrocytes using [35S]-sulfate (5 mCi/ml) as radioligand and adding IL-1alpha (5 ng/ml) incubated for 10h: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA834174
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.51 | 1.68 | 1.68 |
| 445.50 | 1.55 | 1.55 |
| 422.46 | 0.47 | 0.47 |
| 421.48 | 1.07 | 1.07 |