Basic Information
ID: ALA840703
Type: Binding
Description: Selectivity determined as ratio of IC50 of PDE6 against that of PDE5
Activity Charts
Bioactivity
Activity Types for Assay ALA840703
Selectivity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 442.91 | 2.22 | 2.22 |
| 456.51 | 2.78 | 2.78 |
| 479.97 | 3.87 | 3.87 |
| 524.42 | 3.97 | 3.97 |
| 470.53 | 3.08 | 3.08 |
| 474.36 | 3.28 | 3.28 |
| 429.91 | 3.26 | 3.26 |
| 443.94 | 3.56 | 3.56 |
| 488.39 | 3.67 | 3.67 |
| 385.47 | 3.26 | 3.26 |
| 465.94 | 3.56 | 3.56 |
| 510.39 | 3.67 | 3.67 |
| 469.98 | 4.56 | 4.56 |
| 469.55 | 3.82 | 3.82 |
| 490.01 | 4.76 | 4.76 |
| 440.55 | 3.68 | 3.68 |
| 455.56 | 4.10 | 4.10 |
| 459.98 | 4.75 | 4.75 |
| 439.56 | 4.40 | 4.40 |
| 411.53 | 3.32 | 3.32 |
| 394.44 | 1.31 | 1.31 |
| 425.54 | 4.10 | 4.10 |
| 390.45 | 2.38 | 2.38 |
| 409.49 | 2.91 | 2.91 |
| 399.88 | 3.17 | 3.17 |
| 419.41 | 3.23 | 3.23 |
| 366.43 | 1.79 | 1.79 |
| 456.93 | 2.53 | 2.53 |
| 423.47 | 2.30 | 2.30 |
| 425.56 | 3.62 | 3.62 |
| 428.88 | 1.96 | 1.96 |
| 473.33 | 2.07 | 2.07 |
| 465.56 | 3.91 | 3.91 |
| 487.36 | 2.37 | 2.37 |
| 430.31 | 2.97 | 2.97 |
| 542.04 | 5.13 | 5.13 |
| 478.94 | 2.65 | 2.65 |
| 433.43 | 3.53 | 3.53 |
| 365.44 | 2.51 | 2.51 |
| 451.53 | 3.61 | 3.61 |
| 435.53 | 3.90 | 3.90 |
| 441.54 | 3.80 | 3.80 |
| 444.33 | 3.28 | 3.28 |
| 392.42 | 3.15 | 3.15 |
| 395.46 | 2.61 | 2.61 |
| 415.88 | 2.87 | 2.87 |
| 460.33 | 2.98 | 2.98 |
| 429.91 | 3.17 | 3.17 |
| 492.97 | 2.96 | 2.96 |
| 335.41 | 2.57 | 2.57 |
| 408.46 | 1.61 | 1.61 |
| 474.59 | 1.61 | 1.61 |