Basic Information
ID: ALA843460
Type: Functional
Description: Antagonism of opioid analgesia using a mouse writhing model to block morphine (2.5 mg/kg) induced mu-opioid receptor (subcutaneously dosed)
Format: BAO_0000218
Target: Mu opioid receptor(ALA2858)
Document: ALA1126828
Antagonism of opioid analgesia using a mouse writhing model to block morphine (2.5 mg/kg) induced mu-opioid receptor (subcutaneously dosed): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA843460
AD50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.38 | 1.30 | 1.30 |
| 341.41 | 1.53 | 1.53 |
| 315.48 | 4.30 | 4.30 |
| 339.48 | 4.46 | 4.46 |
| 327.44 | 4.37 | 4.37 |
| 325.45 | 4.07 | 4.07 |
| 337.51 | 5.01 | 5.01 |
| 329.51 | 4.69 | 4.69 |
| 303.49 | 4.96 | 4.96 |
| 329.51 | 4.69 | 4.69 |
| 285.39 | 3.78 | 3.78 |
| 289.42 | 3.17 | 3.17 |
| 285.39 | 3.78 | 3.78 |
| 323.48 | 4.62 | 4.62 |
| 345.51 | 4.18 | 4.18 |
| 339.48 | 3.60 | 3.60 |
| 337.46 | 4.26 | 4.26 |
| 233.35 | 3.01 | 3.01 |
| 289.46 | 4.57 | 4.57 |
| 337.51 | 4.93 | 4.93 |
| 337.51 | 4.93 | 4.93 |
| 323.48 | 4.54 | 4.54 |
| 343.54 | 5.08 | 5.08 |
| 329.51 | 4.69 | 4.69 |
| 313.44 | 4.22 | 4.22 |
| 359.51 | 5.39 | 5.39 |
| 357.93 | 5.28 | 5.28 |
| 353.51 | 4.63 | 4.63 |
| 310.44 | 3.63 | 3.63 |
| 343.90 | 4.89 | 4.89 |
| 343.90 | 4.89 | 4.89 |
| 295.43 | 4.19 | 4.19 |
| 323.48 | 4.54 | 4.54 |
| 275.44 | 4.18 | 4.18 |
| 323.48 | 4.54 | 4.54 |
| 259.39 | 3.40 | 3.40 |
| 245.37 | 3.18 | 3.18 |
| 219.33 | 2.62 | 2.62 |
| 325.45 | 3.73 | 3.73 |
| 351.53 | 5.58 | 5.58 |
| 309.45 | 4.23 | 4.23 |
| 339.48 | 4.12 | 4.12 |