Basic Information
ID: ALA845189
Type: Functional
Description: Inhibition of TNF-alpha-induced VCAM-1 expression
Format: BAO_0000019
Target: Tumor necrosis factor receptor R1(ALA3378)
Document: ALA1147634
Inhibition of TNF-alpha-induced VCAM-1 expression: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA845189
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 208.26 | 3.58 | 3.58 |
| 298.34 | 3.61 | 3.61 |
| 238.29 | 3.59 | 3.59 |
| 268.31 | 3.60 | 3.60 |
| 326.37 | 5.59 | 5.59 |
| 350.44 | 5.33 | 5.33 |
| 380.47 | 5.34 | 5.34 |
| 244.24 | 3.86 | 3.86 |
| 410.49 | 5.35 | 5.35 |
| 380.47 | 5.34 | 5.34 |
| 460.55 | 6.50 | 6.50 |
| 400.50 | 6.48 | 6.48 |
| 350.44 | 5.33 | 5.33 |
| 432.47 | 3.65 | 3.65 |
| 364.42 | 5.05 | 5.05 |
| 530.64 | 7.29 | 7.29 |
| 479.37 | 5.56 | 5.56 |
| 524.57 | 5.22 | 5.22 |
| 440.52 | 5.35 | 5.35 |
| 437.29 | 4.39 | 4.39 |
| 513.38 | 5.96 | 5.96 |
| 437.29 | 4.39 | 4.39 |
| 490.58 | 6.51 | 6.51 |
| 336.48 | 5.88 | 5.88 |
| 380.53 | 6.19 | 6.19 |
| 366.50 | 5.89 | 5.89 |
| 350.50 | 6.19 | 6.19 |
| 457.55 | 6.30 | 6.30 |
| 298.34 | 3.61 | 3.61 |
| 298.34 | 3.61 | 3.61 |
| 490.58 | 6.51 | 6.51 |
| 460.55 | 6.50 | 6.50 |
| 482.55 | 5.56 | 5.56 |
| 424.52 | 5.65 | 5.65 |
| 424.52 | 5.65 | 5.65 |
| 394.49 | 5.65 | 5.65 |
| 380.47 | 5.34 | 5.34 |
| 298.34 | 3.61 | 3.61 |
| 380.47 | 5.34 | 5.34 |
| 380.47 | 5.34 | 5.34 |
| 490.51 | 5.36 | 5.36 |
| 554.59 | 5.23 | 5.23 |
| 378.45 | 5.36 | 5.36 |
| 378.45 | 5.36 | 5.36 |
| 407.26 | 4.38 | 4.38 |
| 394.49 | 5.65 | 5.65 |
| 430.53 | 6.49 | 6.49 |
| 320.41 | 5.32 | 5.32 |
| 454.48 | 4.80 | 4.80 |
| 410.49 | 5.35 | 5.35 |
| 298.34 | 3.61 | 3.61 |
| 446.50 | 5.49 | 5.49 |
| 520.53 | 5.37 | 5.37 |
| 494.54 | 5.21 | 5.21 |
| 470.54 | 5.27 | 5.27 |
| 382.46 | 5.86 | 5.86 |
| 356.39 | 5.60 | 5.60 |
| 494.54 | 5.31 | 5.31 |
| 457.55 | 6.30 | 6.30 |
| 494.54 | 5.21 | 5.21 |
| 508.52 | 4.93 | 4.93 |
| 439.30 | 4.31 | 4.31 |
| 409.28 | 4.30 | 4.30 |
| 437.29 | 4.39 | 4.39 |
| 476.55 | 6.20 | 6.20 |
| 490.50 | 6.58 | 6.58 |
| 444.51 | 5.94 | 5.94 |
| 490.60 | 6.66 | 6.66 |
| 577.66 | 3.69 | 3.69 |
| 528.63 | 7.08 | 7.08 |
| 457.55 | 6.30 | 6.30 |
| 502.59 | 6.72 | 6.72 |
| 571.70 | 8.25 | 8.25 |
| 484.53 | 4.81 | 4.81 |
| 454.50 | 4.80 | 4.80 |
| 500.57 | 6.61 | 6.61 |
| 471.58 | 6.49 | 6.49 |
| 426.45 | 3.70 | 3.70 |
| 366.44 | 5.03 | 5.03 |