Basic Information
ID: ALA847342
Type: Binding
Description: Ratio of binding affinity for mutant (C59R+S108N+I164L) to that of wild type dihydrofolate reductase
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA847342
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 251.72 | 1.53 | 1.53 |
| 248.72 | 2.52 | 2.52 |
| 237.69 | 1.14 | 1.14 |
| 228.30 | 2.18 | 2.18 |
| 214.27 | 1.87 | 1.87 |
| 368.87 | 4.15 | 4.15 |
| 398.89 | 3.99 | 3.99 |
| 283.16 | 3.18 | 3.18 |
| 248.72 | 2.52 | 2.52 |
| 270.38 | 3.43 | 3.43 |
| 286.33 | 1.80 | 1.80 |
| 338.84 | 4.14 | 4.14 |
| 320.78 | 2.46 | 2.46 |
| 338.84 | 4.14 | 4.14 |
| 320.78 | 2.46 | 2.46 |
| 234.69 | 2.27 | 2.27 |
| 258.28 | 1.60 | 1.60 |
| 304.40 | 3.48 | 3.48 |
| 251.72 | 1.53 | 1.53 |
| 299.76 | 2.49 | 2.49 |
| 299.77 | 2.49 | 2.49 |
| 237.69 | 1.14 | 1.14 |
| 382.85 | 3.75 | 3.75 |
| 348.41 | 3.10 | 3.10 |
| 391.86 | 4.28 | 4.28 |
| 391.86 | 4.28 | 4.28 |
| 391.86 | 4.28 | 4.28 |
| 391.86 | 4.28 | 4.28 |
| 459.86 | 5.30 | 5.30 |
| 460.75 | 5.59 | 5.59 |
| 279.78 | 2.16 | 2.16 |
| 321.86 | 3.48 | 3.48 |
| 279.78 | 2.31 | 2.31 |
| 279.78 | 2.31 | 2.31 |
| 279.78 | 2.16 | 2.16 |
| 412.88 | 4.25 | 4.25 |
| 278.74 | 1.89 | 1.89 |
| 426.31 | 4.93 | 4.93 |
| 286.33 | 1.80 | 1.80 |
| 244.30 | 1.23 | 1.23 |
| 405.89 | 4.07 | 4.07 |
| 405.89 | 4.07 | 4.07 |
| 357.85 | 3.28 | 3.28 |
| 426.31 | 4.93 | 4.93 |
| 320.78 | 2.46 | 2.46 |
| 553.28 | 6.30 | 6.30 |
| 321.86 | 3.48 | 3.48 |
| 321.86 | 3.48 | 3.48 |