ID: ALA848232
Type: Binding
Description: Ratio of Inhibition of the S108N mutant of dihydrofolate reductase (DHFR) to inhibition of wild type dihydrofolate reductase.
Organism: Plasmodium falciparum
Bioactivity
Activity Types for Assay ALA848232
Ratio
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
248.72 | 2.52 | 2.52 |
270.38 | 3.17 | 3.17 |
228.30 | 2.18 | 2.18 |
293.17 | 2.63 | 2.63 |
502.57 | 4.42 | 4.42 |
426.52 | 4.70 | 4.70 |
454.53 | 3.63 | 3.63 |
283.16 | 3.18 | 3.18 |
440.55 | 4.95 | 4.95 |
412.49 | 4.39 | 4.39 |
468.55 | 4.02 | 4.02 |
440.50 | 3.24 | 3.24 |
396.45 | 2.84 | 2.84 |
214.27 | 1.87 | 1.87 |
244.30 | 1.88 | 1.88 |
368.87 | 4.15 | 4.15 |
290.37 | 3.54 | 3.54 |
350.42 | 3.21 | 3.21 |
364.45 | 3.25 | 3.25 |
398.89 | 3.99 | 3.99 |
283.16 | 3.18 | 3.18 |
248.72 | 2.52 | 2.52 |
234.69 | 2.27 | 2.27 |
270.38 | 3.43 | 3.43 |
286.33 | 1.80 | 1.80 |
200.25 | 1.62 | 1.62 |
220.66 | 1.96 | 1.96 |
338.84 | 4.14 | 4.14 |
320.78 | 2.46 | 2.46 |
416.12 | 3.79 | 3.79 |
426.47 | 2.85 | 2.85 |
186.22 | 1.31 | 1.31 |
338.84 | 4.14 | 4.14 |
320.78 | 2.46 | 2.46 |
234.69 | 2.27 | 2.27 |
220.66 | 1.96 | 1.96 |
453.76 | 5.04 | 5.04 |
419.31 | 4.76 | 4.76 |
258.28 | 1.60 | 1.60 |
304.40 | 3.48 | 3.48 |