Basic Information
ID: ALA852975
Type: Binding
Description: Inhibition of MetAP2 in presence of 40 mg/ml human serum albumin
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA852975
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 437.52 | 4.07 | 4.07 |
| 451.55 | 4.11 | 4.11 |
| 494.06 | 4.86 | 4.86 |
| 473.64 | 4.52 | 4.52 |
| 452.57 | 3.86 | 3.86 |
| 434.58 | 3.72 | 3.72 |
| 450.58 | 2.73 | 2.73 |
| 469.61 | 3.33 | 3.33 |
| 442.58 | 4.42 | 4.42 |
| 451.55 | 4.11 | 4.11 |
| 471.58 | 3.49 | 3.49 |
| 478.64 | 3.51 | 3.51 |
| 496.63 | 3.65 | 3.65 |
| 460.57 | 4.56 | 4.56 |
| 428.55 | 4.03 | 4.03 |
| 443.57 | 3.48 | 3.48 |
| 429.54 | 3.09 | 3.09 |
| 477.60 | 4.35 | 4.35 |
| 477.60 | 4.35 | 4.35 |
| 500.62 | 3.67 | 3.67 |
| 468.57 | 2.87 | 2.87 |
| 476.66 | 4.89 | 4.89 |
| 444.55 | 3.00 | 3.00 |
| 443.57 | 3.48 | 3.48 |
| 443.57 | 3.62 | 3.62 |
| 502.59 | 2.52 | 2.52 |
| 516.62 | 2.91 | 2.91 |
| 554.76 | 4.82 | 4.82 |
| 514.65 | 4.06 | 4.06 |
| 489.59 | 3.95 | 3.95 |
| 499.68 | 5.13 | 5.13 |
| 462.64 | 4.50 | 4.50 |
| 456.61 | 4.81 | 4.81 |
| 470.64 | 5.20 | 5.20 |
| 472.65 | 5.12 | 5.12 |
| 416.54 | 3.56 | 3.56 |
| 457.60 | 3.96 | 3.96 |
| 291.33 | 2.49 | 2.49 |
| 473.60 | 3.73 | 3.73 |
| 487.62 | 4.12 | 4.12 |
| 454.59 | 4.56 | 4.56 |
| 472.58 | 4.70 | 4.70 |
| 474.60 | 4.65 | 4.65 |
| 446.54 | 3.87 | 3.87 |
| 519.67 | 5.14 | 5.14 |
| 540.73 | 4.43 | 4.43 |
| 485.61 | 3.88 | 3.88 |
| 499.63 | 4.27 | 4.27 |
| 456.61 | 4.81 | 4.81 |
| 474.60 | 4.95 | 4.95 |
| 331.39 | 3.06 | 3.06 |
| 525.72 | 5.66 | 5.66 |
| 485.65 | 4.74 | 4.74 |
| 488.61 | 3.53 | 3.53 |
| 500.62 | 3.67 | 3.67 |
| 440.57 | 4.17 | 4.17 |
| 457.60 | 3.82 | 3.82 |
| 540.73 | 4.28 | 4.28 |
| 487.62 | 3.53 | 3.53 |
| 501.65 | 3.92 | 3.92 |
| 442.58 | 4.42 | 4.42 |
| 459.57 | 3.34 | 3.34 |
| 533.67 | 4.44 | 4.44 |
| 515.68 | 4.30 | 4.30 |
| 527.61 | 5.23 | 5.23 |
| 445.59 | 3.82 | 3.82 |
| 444.60 | 4.34 | 4.34 |
| 462.59 | 4.48 | 4.48 |
| 487.67 | 4.99 | 4.99 |
| 346.41 | 2.65 | 2.65 |
| 460.60 | 4.18 | 4.18 |
| 458.62 | 4.73 | 4.73 |
| 485.65 | 4.60 | 4.60 |
| 539.74 | 5.91 | 5.91 |
| 458.58 | 3.93 | 3.93 |
| 473.60 | 3.14 | 3.14 |
| 494.06 | 4.86 | 4.86 |
| 494.06 | 4.86 | 4.86 |
| 485.61 | 3.28 | 3.28 |
| 485.61 | 3.28 | 3.28 |
| 458.56 | 4.31 | 4.31 |
| 458.58 | 3.39 | 3.39 |
| 454.55 | 3.76 | 3.76 |
| 512.05 | 5.00 | 5.00 |
| 473.64 | 4.52 | 4.52 |
| 480.63 | 4.64 | 4.64 |
| 471.62 | 4.35 | 4.35 |
| 473.60 | 3.20 | 3.20 |
| 443.57 | 3.57 | 3.57 |
| 486.64 | 3.11 | 3.11 |
| 459.61 | 4.06 | 4.06 |
| 491.61 | 2.15 | 2.15 |
| 431.56 | 3.48 | 3.48 |
| 447.56 | 2.45 | 2.45 |
| 503.62 | 4.39 | 4.39 |
| 517.65 | 4.73 | 4.73 |
| 403.50 | 2.83 | 2.83 |
| 417.53 | 3.04 | 3.04 |
| 473.64 | 4.60 | 4.60 |
| 445.59 | 3.82 | 3.82 |
| 431.56 | 3.43 | 3.43 |
| 459.61 | 4.21 | 4.21 |
| 515.72 | 5.77 | 5.77 |
| 432.52 | 3.78 | 3.78 |
| 414.53 | 3.64 | 3.64 |
| 457.60 | 3.96 | 3.96 |
| 442.58 | 4.42 | 4.42 |
| 456.61 | 4.81 | 4.81 |
| 470.64 | 5.20 | 5.20 |