Efficacy against human recombinant GABA-Aalpha3 plus beta-3-gamma-2 receptor expressed in L(tk-) cells assessed as modulation of chloride ion by whole...

Basic Information

ID: ALA853519

Type: Functional

Description: Efficacy against human recombinant GABA-Aalpha3 plus beta-3-gamma-2 receptor expressed in L(tk-) cells assessed as modulation of chloride ion by whole cell patch clamp method relative to chlorodiazepoxide

Format: BAO_0000219

Organism: Homo sapiens

Target: GABA-A receptor; alpha-3/beta-3/gamma-2(ALA2094120)

Document: ALA1138896

Efficacy against human recombinant GABA-Aalpha3 plus beta-3-gamma-2 receptor expressed in L(tk-) cells assessed as modulation of chloride ion by whole cell patch clamp method relative to chlorodiazepoxide: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA853519

Efficacy

Total(33)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
401.41	3.30	3.30
419.40	3.44	3.44
419.40	3.44	3.44
435.85	3.96	3.96
435.85	3.96	3.96
426.42	3.18	3.18
437.39	3.58	3.58
419.40	3.44	3.44
437.39	3.58	3.58
437.39	3.58	3.58
419.40	3.44	3.44
437.39	3.58	3.58
437.39	3.58	3.58
437.39	3.58	3.58
407.43	3.37	3.37
455.38	3.72	3.72
365.37	2.52	2.52
469.40	4.32	4.32
407.43	3.37	3.37
391.37	2.90	2.90
455.38	3.72	3.72
431.43	2.80	2.80
416.42	2.89	2.89
402.39	2.70	2.70
435.85	3.96	3.96
402.39	2.70	2.70
419.40	3.44	3.44
402.39	2.70	2.70
402.39	2.70	2.70
404.39	1.31	1.31
391.37	2.90	2.90
391.37	2.90	2.90
389.44	3.23	3.23