Basic Information
ID: ALA855766
Type: Functional
Description: Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FLIPR assay
Organism: Homo sapiens
Cell type: CHO/Galpha16
Activity Charts
Bioactivity
Activity Types for Assay ALA855766
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 479.60 | 4.16 | 4.16 |
| 493.63 | 4.47 | 4.47 |
| 432.50 | 4.90 | 4.90 |
| 493.63 | 4.47 | 4.47 |
| 497.59 | 4.30 | 4.30 |
| 493.63 | 4.47 | 4.47 |
| 457.57 | 4.92 | 4.92 |
| 443.59 | 5.28 | 5.28 |
| 457.60 | 3.65 | 3.65 |
| 507.66 | 4.72 | 4.72 |
| 551.59 | 5.08 | 5.08 |
| 471.62 | 4.04 | 4.04 |
| 535.71 | 5.50 | 5.50 |
| 483.59 | 2.90 | 2.90 |
| 529.06 | 4.52 | 4.52 |
| 485.65 | 4.43 | 4.43 |
| 494.62 | 3.86 | 3.86 |
| 481.58 | 2.95 | 2.95 |
| 485.65 | 4.43 | 4.43 |
| 500.67 | 3.19 | 3.19 |
| 535.71 | 5.46 | 5.46 |
| 480.59 | 3.56 | 3.56 |
| 480.59 | 3.56 | 3.56 |
| 552.70 | 4.23 | 4.23 |
| 549.74 | 5.89 | 5.89 |
| 469.56 | 3.75 | 3.75 |
| 482.56 | 3.39 | 3.39 |
| 487.62 | 3.27 | 3.27 |
| 473.64 | 4.28 | 4.28 |
| 580.75 | 5.01 | 5.01 |
| 578.74 | 4.77 | 4.77 |
| 622.79 | 4.78 | 4.78 |
| 640.81 | 5.73 | 5.73 |
| 473.64 | 4.28 | 4.28 |
| 521.68 | 5.04 | 5.04 |
| 535.69 | 5.38 | 5.38 |
| 539.70 | 4.19 | 4.19 |
| 497.59 | 4.30 | 4.30 |
| 585.73 | 5.74 | 5.74 |
| 443.57 | 3.26 | 3.26 |
| 497.59 | 4.30 | 4.30 |