Basic Information
ID: ALA856036
Type: Functional
Description: IC50 evaluated by measuring contraction and relaxation of guinea pig bladder strips with KCl and glibenclamide respectively
Format: BAO_0000019
Organism: Cavia porcellus
Target: Sulfonylurea receptors; K-ATP channels(ALA2095152)
Document: ALA1129399
IC50 evaluated by measuring contraction and relaxation of guinea pig bladder strips with KCl and glibenclamide respectively: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA856036
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 337.30 | 3.17 | 3.17 |
| 286.33 | 1.75 | 1.75 |
| 337.30 | 3.17 | 3.17 |
| 371.74 | 3.82 | 3.82 |
| 374.34 | 2.17 | 2.17 |
| 337.30 | 3.17 | 3.17 |
| 353.30 | 2.88 | 2.88 |
| 343.33 | 3.23 | 3.23 |
| 374.34 | 2.17 | 2.17 |
| 355.29 | 3.31 | 3.31 |
| 355.29 | 3.31 | 3.31 |
| 390.34 | 1.87 | 1.87 |
| 367.32 | 3.18 | 3.18 |
| 389.35 | 2.48 | 2.48 |
| 389.35 | 2.48 | 2.48 |
| 418.35 | 2.68 | 2.68 |
| 366.36 | 3.96 | 3.96 |
| 389.35 | 2.48 | 2.48 |
| 418.35 | 2.68 | 2.68 |
| 441.35 | 3.79 | 3.79 |
| 452.25 | 3.53 | 3.53 |
| 407.80 | 3.42 | 3.42 |
| 417.36 | 2.47 | 2.47 |
| 386.35 | 4.00 | 4.00 |
| 355.29 | 3.31 | 3.31 |
| 464.47 | 4.47 | 4.47 |
| 417.36 | 2.47 | 2.47 |
| 418.35 | 2.68 | 2.68 |
| 355.29 | 3.31 | 3.31 |
| 418.35 | 2.68 | 2.68 |
| 353.30 | 2.88 | 2.88 |
| 375.33 | 1.56 | 1.56 |
| 362.31 | 3.04 | 3.04 |
| 375.33 | 1.56 | 1.56 |
| 374.34 | 2.17 | 2.17 |
| 403.38 | 2.78 | 2.78 |
| 433.37 | 3.58 | 3.58 |
| 380.37 | 2.23 | 2.23 |
| 374.34 | 2.17 | 2.17 |
| 374.34 | 2.17 | 2.17 |
| 374.34 | 2.17 | 2.17 |
| 407.80 | 3.42 | 3.42 |
| 403.38 | 2.78 | 2.78 |
| 403.38 | 2.78 | 2.78 |
| 380.37 | 2.23 | 2.23 |
| 339.31 | 3.02 | 3.02 |
| 351.32 | 3.48 | 3.48 |
| 403.38 | 2.78 | 2.78 |
| 363.29 | 2.71 | 2.71 |
| 416.19 | 3.93 | 3.93 |
| 351.32 | 3.48 | 3.48 |
| 355.29 | 3.31 | 3.31 |
| 398.36 | 2.64 | 2.64 |
| 373.35 | 2.77 | 2.77 |
| 398.36 | 2.64 | 2.64 |
| 398.36 | 2.64 | 2.64 |
| 391.34 | 2.91 | 2.91 |
| 391.34 | 2.91 | 2.91 |
| 391.34 | 2.91 | 2.91 |
| 398.36 | 2.64 | 2.64 |
| 389.35 | 2.48 | 2.48 |
| 371.34 | 2.75 | 2.75 |
| 399.35 | 2.32 | 2.32 |
| 352.29 | 0.71 | 0.71 |
| 387.38 | 3.08 | 3.08 |
| 338.26 | 0.37 | 0.37 |
| 351.32 | 3.48 | 3.48 |
| 371.74 | 3.82 | 3.82 |
| 366.34 | 3.34 | 3.34 |
| 391.34 | 2.91 | 2.91 |
| 373.35 | 2.77 | 2.77 |
| 402.39 | 2.76 | 2.76 |
| 441.35 | 3.79 | 3.79 |
| 387.38 | 3.08 | 3.08 |
| 387.38 | 3.08 | 3.08 |
| 387.38 | 3.08 | 3.08 |
| 407.80 | 3.42 | 3.42 |