Basic Information
ID: ALA856122
Type: Binding
Description: Inhibitory activity at 10 uM against 17-beta-hydroxysteroid dehydrogenase type 2 in MDAMB-231 human breast cancer cells using 2 nM [3H]estradiol
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Cancer cell lines
Target: Estradiol 17-beta-dehydrogenase 2(ALA2789)
Document: ALA1141073
Inhibitory activity at 10 uM against 17-beta-hydroxysteroid dehydrogenase type 2 in MDAMB-231 human breast cancer cells using 2 nM [3H]estradiol: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA856122
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 298.38 | 3.87 | 3.87 |
| 370.45 | 3.80 | 3.80 |
| 347.46 | 4.07 | 4.07 |
| 308.43 | 3.70 | 3.70 |
| 350.51 | 4.81 | 4.81 |
| 366.46 | 3.33 | 3.33 |
| 352.48 | 3.81 | 3.81 |
| 362.39 | 4.70 | 4.70 |
| 366.46 | 3.86 | 3.86 |
| 338.41 | 3.38 | 3.38 |
| 324.42 | 3.18 | 3.18 |
| 351.45 | 3.04 | 3.04 |
| 379.50 | 3.82 | 3.82 |
| 379.50 | 3.78 | 3.78 |
| 421.54 | 3.59 | 3.59 |
| 430.55 | 3.95 | 3.95 |
| 449.60 | 2.62 | 2.62 |
| 443.55 | 3.71 | 3.71 |
| 428.54 | 4.01 | 4.01 |
| 428.54 | 4.01 | 4.01 |
| 442.56 | 4.05 | 4.05 |
| 305.42 | 4.36 | 4.36 |
| 294.40 | 3.69 | 3.69 |
| 308.43 | 3.70 | 3.70 |
| 350.51 | 4.81 | 4.81 |
| 366.46 | 3.33 | 3.33 |
| 352.48 | 3.81 | 3.81 |
| 298.43 | 4.45 | 4.45 |
| 299.37 | 3.26 | 3.26 |
| 314.38 | 3.52 | 3.52 |
| 295.38 | 3.57 | 3.57 |
| 309.41 | 3.96 | 3.96 |