Basic Information
ID: ALA857689
Type: Binding
Description: Affinity for human neuropeptide Y receptor Y5, binding was evaluated in an in vitro radioligand [125I]PYY binding assay
Activity Charts
Bioactivity
Activity Types for Assay ALA857689
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 306.29 | 3.91 | 3.91 |
| 314.39 | 4.55 | 4.55 |
| 334.47 | 4.81 | 4.81 |
| 326.83 | 4.58 | 4.58 |
| 337.43 | 2.68 | 2.68 |
| 350.51 | 5.90 | 5.90 |
| 326.83 | 4.58 | 4.58 |
| 326.83 | 4.58 | 4.58 |
| 293.37 | 2.34 | 2.34 |
| 291.40 | 4.53 | 4.53 |
| 310.38 | 4.06 | 4.06 |
| 280.37 | 3.73 | 3.73 |
| 318.38 | 4.40 | 4.40 |
| 346.36 | 4.63 | 4.63 |
| 310.40 | 3.72 | 3.72 |
| 335.41 | 2.55 | 2.55 |
| 294.36 | 2.77 | 2.77 |
| 290.37 | 3.70 | 3.70 |
| 312.46 | 4.33 | 4.33 |
| 276.34 | 3.31 | 3.31 |
| 286.34 | 4.00 | 4.00 |
| 291.38 | 4.66 | 4.66 |
| 291.40 | 4.98 | 4.98 |
| 318.38 | 4.11 | 4.11 |
| 354.46 | 5.23 | 5.23 |
| 371.47 | 2.01 | 2.01 |
| 336.44 | 3.81 | 3.81 |
| 374.41 | 4.82 | 4.82 |
| 350.51 | 4.72 | 4.72 |
| 293.37 | 3.32 | 3.32 |
| 320.44 | 4.65 | 4.65 |
| 360.38 | 4.94 | 4.94 |
| 310.38 | 4.06 | 4.06 |
| 360.38 | 4.94 | 4.94 |
| 306.41 | 4.26 | 4.26 |
| 310.38 | 4.06 | 4.06 |
| 320.44 | 4.65 | 4.65 |
| 360.38 | 4.94 | 4.94 |
| 310.38 | 4.06 | 4.06 |
| 292.39 | 3.92 | 3.92 |
| 296.37 | 3.78 | 3.78 |
| 320.44 | 4.74 | 4.74 |
| 278.36 | 3.57 | 3.57 |
| 318.42 | 4.44 | 4.44 |
| 320.44 | 4.57 | 4.57 |
| 300.37 | 4.68 | 4.68 |
| 224.27 | 2.52 | 2.52 |
| 340.43 | 4.50 | 4.50 |
| 335.45 | 3.42 | 3.42 |
| 294.36 | 2.71 | 2.71 |
| 264.33 | 3.14 | 3.14 |
| 306.41 | 4.18 | 4.18 |
| 286.42 | 3.94 | 3.94 |
| 272.40 | 3.55 | 3.55 |
| 258.37 | 3.16 | 3.16 |
| 306.41 | 4.31 | 4.31 |
| 348.48 | 5.14 | 5.14 |
| 320.44 | 3.99 | 3.99 |
| 278.36 | 3.53 | 3.53 |
| 332.41 | 4.67 | 4.67 |
| 404.92 | 3.84 | 3.84 |
| 322.41 | 3.79 | 3.79 |
| 350.47 | 4.00 | 4.00 |
| 346.36 | 4.34 | 4.34 |
| 328.37 | 4.20 | 4.20 |
| 328.37 | 4.20 | 4.20 |
| 298.43 | 4.26 | 4.26 |
| 324.40 | 3.94 | 3.94 |
| 324.45 | 4.34 | 4.34 |
| 372.93 | 5.15 | 5.15 |
| 322.41 | 3.88 | 3.88 |
| 308.38 | 3.62 | 3.62 |
| 306.41 | 4.18 | 4.18 |
| 397.48 | 4.87 | 4.87 |
| 321.43 | 3.68 | 3.68 |
| 335.46 | 4.44 | 4.44 |
| 328.37 | 4.20 | 4.20 |
| 361.49 | 4.61 | 4.61 |
| 368.48 | 5.59 | 5.59 |
| 306.41 | 4.23 | 4.23 |
| 334.42 | 4.13 | 4.13 |
| 328.37 | 4.20 | 4.20 |
| 368.48 | 5.59 | 5.59 |
| 320.44 | 4.49 | 4.49 |
| 293.37 | 3.32 | 3.32 |
| 371.28 | 4.69 | 4.69 |
| 309.44 | 4.66 | 4.66 |
| 291.40 | 4.53 | 4.53 |
| 293.37 | 4.19 | 4.19 |
| 306.41 | 3.93 | 3.93 |
| 293.37 | 3.20 | 3.20 |
| 336.44 | 3.67 | 3.67 |
| 308.38 | 2.89 | 2.89 |
| 349.48 | 3.81 | 3.81 |
| 320.44 | 4.37 | 4.37 |
| 307.40 | 3.66 | 3.66 |
| 282.35 | 3.52 | 3.52 |
| 230.31 | 2.52 | 2.52 |
| 298.42 | 3.99 | 3.99 |
| 322.41 | 3.93 | 3.93 |