Basic Information
ID: ALA858334
Type: Binding
Description: Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)
Activity Charts
Bioactivity
Activity Types for Assay ALA858334
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.37 | 4.25 | 4.25 |
| 399.37 | 3.65 | 3.65 |
| 415.82 | 4.17 | 4.17 |
| 465.28 | 5.28 | 5.28 |
| 476.27 | 3.98 | 3.98 |
| 431.82 | 3.87 | 3.87 |
| 415.37 | 3.35 | 3.35 |
| 398.38 | 4.41 | 4.41 |
| 394.42 | 4.58 | 4.58 |
| 402.34 | 4.24 | 4.24 |
| 346.84 | 3.90 | 3.90 |
| 366.36 | 3.96 | 3.96 |
| 446.90 | 5.34 | 5.34 |
| 430.83 | 4.62 | 4.62 |
| 398.38 | 4.41 | 4.41 |
| 414.84 | 4.92 | 4.92 |
| 478.32 | 5.33 | 5.33 |
| 396.39 | 3.97 | 3.97 |
| 398.38 | 4.41 | 4.41 |
| 385.34 | 3.34 | 3.34 |
| 427.42 | 4.17 | 4.17 |
| 443.88 | 4.68 | 4.68 |
| 381.38 | 3.51 | 3.51 |
| 414.38 | 4.11 | 4.11 |
| 381.38 | 3.51 | 3.51 |
| 446.25 | 3.97 | 3.97 |
| 435.25 | 5.27 | 5.27 |
| 380.39 | 4.27 | 4.27 |
| 414.38 | 4.11 | 4.11 |
| 384.35 | 4.10 | 4.10 |
| 400.81 | 4.62 | 4.62 |
| 404.88 | 3.77 | 3.77 |
| 445.26 | 4.72 | 4.72 |
| 414.84 | 4.92 | 4.92 |
| 357.82 | 3.47 | 3.47 |
| 384.35 | 4.10 | 4.10 |
| 400.81 | 4.62 | 4.62 |
| 384.35 | 4.10 | 4.10 |
| 330.38 | 3.39 | 3.39 |
| 410.37 | 3.69 | 3.69 |
| 443.88 | 4.68 | 4.68 |
| 430.84 | 4.62 | 4.62 |
| 384.35 | 4.10 | 4.10 |
| 380.39 | 4.27 | 4.27 |
| 400.81 | 4.62 | 4.62 |
| 385.34 | 3.34 | 3.34 |
| 401.80 | 3.86 | 3.86 |
| 424.44 | 4.59 | 4.59 |
| 367.35 | 3.21 | 3.21 |
| 385.34 | 3.34 | 3.34 |
| 554.18 | 5.50 | 5.50 |
| 415.82 | 4.17 | 4.17 |
| 447.89 | 4.58 | 4.58 |
| 403.33 | 3.48 | 3.48 |
| 473.38 | 5.83 | 5.83 |
| 434.36 | 4.98 | 4.98 |
| 364.83 | 4.07 | 4.07 |
| 433.36 | 3.49 | 3.49 |
| 382.82 | 4.53 | 4.53 |
| 360.82 | 3.41 | 3.41 |
| 395.41 | 4.00 | 4.00 |
| 381.38 | 3.51 | 3.51 |
| 415.37 | 3.35 | 3.35 |
| 371.85 | 3.66 | 3.66 |
| 424.93 | 3.14 | 3.14 |
| 401.80 | 3.86 | 3.86 |
| 412.46 | 4.68 | 4.68 |
| 392.93 | 4.46 | 4.46 |
| 489.45 | 6.54 | 6.54 |
| 376.87 | 3.74 | 3.74 |
| 409.43 | 4.03 | 4.03 |
| 410.42 | 4.11 | 4.11 |
| 362.84 | 3.09 | 3.09 |
| 408.91 | 5.26 | 5.26 |
| 409.43 | 4.03 | 4.03 |
| 412.46 | 4.68 | 4.68 |
| 313.38 | 2.65 | 2.65 |
| 382.37 | 2.91 | 2.91 |
| 386.42 | 4.33 | 4.33 |
| 324.37 | 2.21 | 2.21 |
| 382.37 | 2.91 | 2.91 |
| 446.25 | 4.12 | 4.12 |
| 397.38 | 3.37 | 3.37 |
| 372.33 | 2.50 | 2.50 |
| 371.34 | 3.26 | 3.26 |
| 388.40 | 2.97 | 2.97 |
| 368.34 | 2.60 | 2.60 |
| 382.37 | 2.91 | 2.91 |
| 382.37 | 2.91 | 2.91 |
| 329.38 | 1.83 | 1.83 |
| 381.38 | 3.67 | 3.67 |
| 381.38 | 3.67 | 3.67 |
| 367.35 | 3.36 | 3.36 |
| 367.35 | 3.36 | 3.36 |
| 388.40 | 2.97 | 2.97 |
| 381.38 | 3.67 | 3.67 |
| 388.40 | 2.97 | 2.97 |
| 410.37 | 3.69 | 3.69 |
| 387.41 | 3.73 | 3.73 |
| 382.37 | 2.91 | 2.91 |
| 382.37 | 2.91 | 2.91 |
| 382.37 | 2.91 | 2.91 |
| 397.38 | 3.37 | 3.37 |
| 419.43 | 4.45 | 4.45 |
| 417.41 | 4.51 | 4.51 |
| 381.38 | 3.67 | 3.67 |
| 381.38 | 3.67 | 3.67 |
| 381.38 | 3.67 | 3.67 |
| 447.24 | 3.36 | 3.36 |
| 381.38 | 3.67 | 3.67 |
| 417.41 | 4.51 | 4.51 |
| 417.41 | 4.51 | 4.51 |
| 447.94 | 4.01 | 4.01 |