Basic Information
ID: ALA863213
Type: Functional
Description: Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
Organism: Homo sapiens
Cell type: MDCK
Activity Charts
Bioactivity
Activity Types for Assay ALA863213
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.27 | 0.15 | 0.15 |
| 222.24 | -0.24 | -0.24 |
| 248.19 | -2.17 | -2.17 |
| 160.17 | -1.08 | -1.08 |
| 75.07 | -0.97 | -0.97 |
| 303.36 | 1.26 | 1.26 |
| 367.40 | 1.56 | 1.56 |
| 390.44 | 2.33 | 2.33 |
| 117.15 | 0.05 | 0.05 |
| 330.39 | -3.01 | -3.01 |
| 222.24 | -0.24 | -0.24 |
| 228.29 | 0.35 | 0.35 |
| 238.24 | -0.54 | -0.54 |
| 261.28 | 0.24 | 0.24 |
| 172.18 | -1.06 | -1.06 |
| 189.17 | -2.74 | -2.74 |
| 188.23 | -0.44 | -0.44 |
| 132.12 | -1.85 | -1.85 |
| 236.27 | 0.15 | 0.15 |
| 244.34 | 0.98 | 0.98 |
| 216.28 | 0.20 | 0.20 |
| 172.18 | -0.98 | -0.98 |
| 204.18 | -1.62 | -1.62 |
| 190.16 | -2.01 | -2.01 |
| 212.21 | -1.52 | -1.52 |
| 275.31 | 0.63 | 0.63 |
| 203.24 | -1.36 | -1.36 |
| 252.27 | -0.15 | -0.15 |
| 190.16 | -2.01 | -2.01 |
| 252.27 | -0.15 | -0.15 |
| 203.24 | -1.36 | -1.36 |
| 261.28 | 0.24 | 0.24 |
| 146.15 | -1.47 | -1.47 |
| 238.24 | -0.54 | -0.54 |
| 204.18 | -1.62 | -1.62 |
| 212.21 | -1.52 | -1.52 |
| 303.36 | 1.26 | 1.26 |
| 344.37 | 0.78 | 0.78 |
| 276.24 | -1.39 | -1.39 |
| 311.38 | 0.77 | 0.77 |
| 188.19 | -3.34 | -3.34 |
| 332.40 | 0.74 | 0.74 |
| 146.15 | -1.51 | -1.51 |
| 275.31 | -1.12 | -1.12 |
| 230.22 | -1.22 | -1.22 |
| 212.25 | -0.19 | -0.19 |
| 217.27 | -0.97 | -0.97 |
| 275.31 | 0.63 | 0.63 |
| 244.25 | -0.83 | -0.83 |
| 275.31 | -1.12 | -1.12 |
| 243.31 | -0.48 | -0.48 |
| 237.26 | -1.14 | -1.14 |
| 245.32 | -0.33 | -0.33 |
| 231.26 | -2.43 | -2.43 |
| 221.26 | -0.84 | -0.84 |
| 243.31 | -0.56 | -0.56 |
| 202.21 | -1.70 | -1.70 |
| 621.21 | 2.70 | 2.70 |
| 315.41 | 0.34 | 0.34 |
| 246.22 | -3.62 | -3.62 |
| 339.40 | 0.70 | 0.70 |
| 367.41 | 1.56 | 1.56 |
| 302.38 | -1.93 | -1.93 |
| 369.42 | 0.65 | 0.65 |
| 204.18 | -1.62 | -1.62 |
| 319.32 | 0.08 | 0.08 |
| 237.26 | -1.14 | -1.14 |
| 245.28 | -1.32 | -1.32 |
| 292.30 | -1.19 | -1.19 |
| 341.37 | 0.57 | 0.57 |
| 335.40 | 0.29 | 0.29 |
| 232.24 | -0.99 | -0.99 |
| 274.28 | -2.59 | -2.59 |
| 275.26 | -1.99 | -1.99 |
| 274.36 | -0.86 | -0.86 |
| 235.29 | -0.45 | -0.45 |
| 327.38 | 0.47 | 0.47 |
| 302.38 | -1.93 | -1.93 |
| 246.31 | -1.64 | -1.64 |
| 192.17 | -3.13 | -3.13 |
| 343.38 | 0.18 | 0.18 |