Basic Information
ID: ALA864855
Type: Binding
Description: Inhibition of human Wee1 in presence of 9.5 uM ATP
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase WEE1(ALA5491)
Document: ALA1145314
Inhibition of human Wee1 in presence of 9.5 uM ATP: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA864855
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.35 | 3.89 | 3.89 |
| 356.38 | 4.14 | 4.14 |
| 342.35 | 3.89 | 3.89 |
| 404.43 | 5.24 | 5.24 |
| 328.33 | 3.58 | 3.58 |
| 330.34 | 3.43 | 3.43 |
| 252.23 | 1.91 | 1.91 |
| 378.12 | 2.51 | 2.51 |
| 328.33 | 3.58 | 3.58 |
| 328.33 | 3.58 | 3.58 |
| 329.31 | 3.84 | 3.84 |
| 344.37 | 4.08 | 4.08 |
| 314.34 | 3.94 | 3.94 |
| 330.34 | 3.43 | 3.43 |
| 356.38 | 3.93 | 3.93 |
| 329.31 | 4.00 | 4.00 |
| 343.34 | 3.16 | 3.16 |
| 362.77 | 4.23 | 4.23 |
| 376.80 | 4.53 | 4.53 |
| 345.38 | 4.31 | 4.31 |
| 342.35 | 3.59 | 3.59 |
| 342.35 | 3.89 | 3.89 |
| 396.32 | 4.60 | 4.60 |
| 362.77 | 4.23 | 4.23 |
| 334.36 | 3.64 | 3.64 |
| 334.36 | 3.64 | 3.64 |
| 358.35 | 3.07 | 3.07 |
| 357.37 | 3.04 | 3.04 |
| 317.30 | 2.91 | 2.91 |
| 317.30 | 2.91 | 2.91 |
| 372.38 | 3.98 | 3.98 |
| 374.42 | 4.30 | 4.30 |
| 353.34 | 3.45 | 3.45 |
| 321.34 | 1.99 | 1.99 |
| 329.31 | 2.97 | 2.97 |
| 390.42 | 3.31 | 3.31 |
| 373.32 | 3.49 | 3.49 |
| 329.31 | 2.97 | 2.97 |
| 344.33 | 3.28 | 3.28 |
| 358.35 | 3.59 | 3.59 |
| 371.35 | 2.68 | 2.68 |
| 356.38 | 4.19 | 4.19 |
| 356.38 | 4.19 | 4.19 |
| 358.35 | 3.07 | 3.07 |
| 378.77 | 3.94 | 3.94 |
| 373.37 | 3.17 | 3.17 |
| 373.37 | 3.17 | 3.17 |
| 353.34 | 3.45 | 3.45 |
| 404.43 | 5.24 | 5.24 |
| 377.79 | 3.81 | 3.81 |
| 397.22 | 4.88 | 4.88 |
| 388.38 | 3.59 | 3.59 |
| 376.34 | 3.73 | 3.73 |
| 376.80 | 4.24 | 4.24 |
| 378.77 | 3.94 | 3.94 |
| 392.80 | 4.24 | 4.24 |
| 413.22 | 4.59 | 4.59 |
| 363.76 | 4.50 | 4.50 |
| 346.32 | 3.72 | 3.72 |
| 370.36 | 3.78 | 3.78 |
| 342.35 | 3.89 | 3.89 |
| 390.42 | 3.31 | 3.31 |
| 343.34 | 3.16 | 3.16 |
| 422.24 | 3.92 | 3.92 |
| 486.12 | 5.10 | 5.10 |
| 335.36 | 2.38 | 2.38 |
| 390.83 | 4.72 | 4.72 |
| 407.22 | 4.34 | 4.34 |
| 454.22 | 4.18 | 4.18 |
| 370.36 | 3.78 | 3.78 |
| 396.32 | 4.60 | 4.60 |
| 358.35 | 3.07 | 3.07 |
| 397.22 | 4.88 | 4.88 |
| 378.77 | 3.94 | 3.94 |
| 356.38 | 4.19 | 4.19 |
| 404.85 | 5.11 | 5.11 |
| 404.85 | 5.29 | 5.29 |
| 342.35 | 3.89 | 3.89 |
| 356.38 | 4.14 | 4.14 |
| 404.43 | 5.24 | 5.24 |
| 344.33 | 3.28 | 3.28 |
| 353.34 | 3.45 | 3.45 |
| 370.36 | 3.78 | 3.78 |
| 377.79 | 3.81 | 3.81 |
| 378.77 | 3.94 | 3.94 |
| 418.88 | 5.50 | 5.50 |
| 396.32 | 4.60 | 4.60 |
| 343.34 | 3.16 | 3.16 |
| 358.35 | 3.59 | 3.59 |
| 373.32 | 3.49 | 3.49 |
| 344.33 | 3.28 | 3.28 |
| 358.35 | 3.59 | 3.59 |
| 377.79 | 3.81 | 3.81 |
| 397.22 | 4.88 | 4.88 |
| 346.32 | 3.72 | 3.72 |
| 362.77 | 4.23 | 4.23 |
| 343.34 | 3.16 | 3.16 |
| 346.32 | 3.72 | 3.72 |
| 374.42 | 4.30 | 4.30 |
| 413.22 | 4.59 | 4.59 |