Basic Information
ID: ALA869067
Type: Binding
Description: Inhibition of human recombinant DHFR assessed as rate of depletion of NADPH
Format: BAO_0000357
Organism: Homo sapiens
Target: Dihydrofolate reductase(ALA202)
Document: ALA1138039
Inhibition of human recombinant DHFR assessed as rate of depletion of NADPH: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA869067
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.95 | 5.29 | 5.29 |
| 397.50 | 2.89 | 2.89 |
| 420.52 | 3.94 | 3.94 |
| 440.51 | 4.67 | 4.67 |
| 468.56 | 4.39 | 4.39 |
| 524.44 | 5.03 | 5.03 |
| 439.52 | 4.21 | 4.21 |
| 389.46 | 3.37 | 3.37 |
| 417.51 | 4.15 | 4.15 |
| 406.49 | 3.55 | 3.55 |
| 490.63 | 4.33 | 4.33 |
| 498.61 | 4.34 | 4.34 |