Basic Information
ID: ALA870213
Type: Functional
Description: Antagonist activity at human P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of calcium flux by FLIPR
Organism: Homo sapiens
Cell type: 1321-N1
Activity Charts
Bioactivity
Activity Types for Assay ALA870213
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 338.28 | 4.94 | 4.94 |
| 324.15 | 3.09 | 3.09 |
| 319.20 | 4.00 | 4.00 |
| 357.70 | 3.46 | 3.46 |
| 306.16 | 3.09 | 3.09 |
| 306.16 | 3.09 | 3.09 |
| 306.16 | 3.09 | 3.09 |
| 340.60 | 3.74 | 3.74 |
| 333.44 | 3.61 | 3.61 |
| 323.25 | 2.94 | 2.94 |
| 339.71 | 3.46 | 3.46 |
| 323.25 | 2.94 | 2.94 |
| 271.71 | 2.44 | 2.44 |
| 271.71 | 2.44 | 2.44 |
| 306.16 | 3.09 | 3.09 |
| 324.15 | 3.23 | 3.23 |
| 320.18 | 3.40 | 3.40 |
| 320.18 | 3.28 | 3.28 |
| 340.24 | 3.77 | 3.77 |
| 306.16 | 3.09 | 3.09 |
| 278.36 | 3.31 | 3.31 |
| 324.17 | 3.30 | 3.30 |
| 306.16 | 2.95 | 2.95 |
| 339.71 | 3.32 | 3.32 |
| 237.27 | 1.78 | 1.78 |
| 330.78 | 3.06 | 3.06 |
| 237.27 | 1.78 | 1.78 |
| 287.33 | 2.94 | 2.94 |
| 287.33 | 2.94 | 2.94 |
| 305.17 | 3.70 | 3.70 |