Basic Information
ID: ALA873739
Type: Binding
Description: Inhibition of MEK-1 activity
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA873739
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.29 | 3.62 | 3.62 |
| 436.71 | 3.96 | 3.96 |
| 361.25 | 2.99 | 2.99 |
| 402.26 | 3.31 | 3.31 |
| 384.46 | 3.47 | 3.47 |
| 382.49 | 3.27 | 3.27 |
| 396.47 | 2.91 | 2.91 |
| 400.53 | 3.83 | 3.83 |
| 432.53 | 2.51 | 2.51 |
| 410.54 | 4.00 | 4.00 |
| 452.46 | 4.49 | 4.49 |
| 470.45 | 4.63 | 4.63 |
| 486.90 | 5.14 | 5.14 |
| 486.90 | 5.14 | 5.14 |
| 470.45 | 4.63 | 4.63 |
| 427.53 | 3.54 | 3.54 |
| 521.35 | 5.80 | 5.80 |
| 504.89 | 5.28 | 5.28 |
| 470.45 | 4.63 | 4.63 |
| 453.35 | 4.78 | 4.78 |
| 436.90 | 4.26 | 4.26 |
| 471.34 | 4.92 | 4.92 |
| 450.92 | 4.57 | 4.57 |
| 471.34 | 4.92 | 4.92 |
| 453.35 | 4.78 | 4.78 |
| 420.44 | 3.75 | 3.75 |
| 487.80 | 5.43 | 5.43 |
| 436.90 | 4.26 | 4.26 |
| 453.35 | 4.78 | 4.78 |
| 420.44 | 3.75 | 3.75 |
| 436.90 | 4.26 | 4.26 |
| 471.34 | 4.92 | 4.92 |
| 453.35 | 4.78 | 4.78 |
| 420.44 | 3.75 | 3.75 |
| 454.89 | 4.40 | 4.40 |
| 472.88 | 4.54 | 4.54 |
| 450.92 | 4.57 | 4.57 |
| 480.38 | 4.64 | 4.64 |
| 508.43 | 4.73 | 4.73 |
| 522.46 | 5.12 | 5.12 |
| 493.42 | 4.56 | 4.56 |
| 521.47 | 4.64 | 4.64 |
| 535.50 | 5.03 | 5.03 |
| 507.45 | 4.30 | 4.30 |
| 521.43 | 3.83 | 3.83 |
| 439.32 | 4.39 | 4.39 |
| 469.35 | 3.75 | 3.75 |
| 469.35 | 3.75 | 3.75 |
| 483.38 | 4.14 | 4.14 |
| 453.35 | 4.78 | 4.78 |
| 485.35 | 3.68 | 3.68 |
| 481.41 | 5.41 | 5.41 |
| 467.38 | 5.17 | 5.17 |
| 479.39 | 5.58 | 5.58 |
| 436.71 | 3.96 | 3.96 |
| 383.48 | 3.63 | 3.63 |