Basic Information
ID: ALA874890
Type: Functional
Description: MDR-reversal activity evaluated against the resistant human breast tumor cell line MDA-435/LCC6-MDR
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDA-MB-435
Target: MDA-MB-435(ALA614697)
Document: ALA1145206
MDR-reversal activity evaluated against the resistant human breast tumor cell line MDA-435/LCC6-MDR: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA874890
Reduction
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 748.82 | 4.27 | 4.27 |
| 800.85 | 4.42 | 4.42 |
| 836.93 | 6.64 | 6.64 |
| 878.92 | 6.79 | 6.79 |
| 853.00 | 7.00 | 7.00 |
| 710.82 | 4.86 | 4.86 |
| 1283.48 | ||
| 712.84 | 4.78 | 4.78 |
| 1285.50 | ||
| 863.96 | 6.10 | 6.10 |
| 905.95 | 6.25 | 6.25 |
| 864.94 | 6.07 | 6.07 |
| 906.93 | 6.22 | 6.22 |
| 985.83 | 6.98 | 6.98 |
| 951.93 | 6.13 | 6.13 |
| 820.93 | 6.34 | 6.34 |
| 808.92 | 6.04 | 6.04 |
| 771.86 | 4.79 | 4.79 |
| 769.84 | 5.00 | 5.00 |
| 769.84 | 5.00 | 5.00 |
| 798.88 | 5.37 | 5.37 |
| 760.83 | 4.55 | 4.55 |
| 846.97 | 6.91 | 6.91 |
| 891.02 | 7.20 | 7.20 |
| 862.97 | 6.39 | 6.39 |
| 852.97 | 5.85 | 5.85 |
| 836.98 | 6.36 | 6.36 |
| 764.87 | 4.94 | 4.94 |
| 1337.53 | ||
| 912.96 | 6.28 | 6.28 |
| 895.91 | 5.55 | 5.55 |
| 915.00 | 7.22 | 7.22 |
| 894.99 | 7.15 | 7.15 |
| 836.80 | 5.46 | 5.46 |
| 892.95 | 5.73 | 5.73 |
| 868.97 | 5.99 | 5.99 |
| 836.89 | 6.15 | 6.15 |
| 798.88 | 5.37 | 5.37 |
| 890.94 | 6.23 | 6.23 |
| 822.90 | 5.68 | 5.68 |
| 864.90 | 5.83 | 5.83 |
| 880.94 | 5.77 | 5.77 |
| 836.93 | 6.64 | 6.64 |
| 853.00 | 7.00 | 7.00 |
| 864.94 | 6.07 | 6.07 |
| 877.00 | 6.86 | 6.86 |
| 918.99 | 7.01 | 7.01 |
| 879.01 | 6.78 | 6.78 |
| 921.00 | 6.93 | 6.93 |
| 866.93 | 6.22 | 6.22 |
| 915.00 | 7.22 | 7.22 |
| 864.94 | 6.07 | 6.07 |
| 945.97 | 6.70 | 6.70 |
| 864.94 | 6.07 | 6.07 |
| 906.93 | 6.22 | 6.22 |
| 894.97 | 6.08 | 6.08 |
| 892.01 | 6.14 | 6.14 |
| 878.97 | 6.09 | 6.09 |
| 848.94 | 6.08 | 6.08 |
| 894.97 | 6.08 | 6.08 |
| 936.96 | 6.23 | 6.23 |
| 836.93 | 5.61 | 5.61 |
| 878.92 | 5.76 | 5.76 |
| 864.94 | 6.07 | 6.07 |
| 863.96 | 6.10 | 6.10 |
| 984.94 | 8.12 | 8.12 |
| 876.95 | 5.54 | 5.54 |
| 846.93 | 6.06 | 6.06 |
| 911.01 | 7.37 | 7.37 |
| 955.07 | 7.31 | 7.31 |
| 941.04 | 7.87 | 7.87 |
| 937.05 | 7.77 | 7.77 |
| 864.94 | 6.30 | 6.30 |
| 862.97 | 6.47 | 6.47 |
| 766.84 | 5.07 | 5.07 |
| 936.96 | 6.23 | 6.23 |
| 894.97 | 6.08 | 6.08 |
| 936.96 | 6.23 | 6.23 |