Basic Information
ID: ALA875027
Type: Binding
Description: Inhibition of dihydrofolate reductase (DHFR) from Leishmania major
Organism: Leishmania major
Activity Charts
Bioactivity
Activity Types for Assay ALA875027
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 289.34 | 1.05 | 1.05 |
| 247.30 | 0.88 | 0.88 |
| 449.48 | 4.13 | 4.13 |
| 242.29 | 0.74 | 0.74 |
| 285.27 | 1.89 | 1.89 |
| 217.28 | 0.87 | 0.87 |
| 259.31 | 1.07 | 1.07 |
| 323.40 | 2.45 | 2.45 |
| 296.36 | -0.48 | -0.48 |
| 251.72 | 1.53 | 1.53 |
| 273.38 | 2.17 | 2.17 |
| 373.91 | 3.82 | 3.82 |
| 386.36 | ||
| 348.41 | 2.32 | 2.32 |
| 262.27 | 0.78 | 0.78 |
| 233.28 | 0.58 | 0.58 |
| 381.52 | 3.47 | 3.47 |
| 421.42 | 3.35 | 3.35 |
| 408.47 | 0.68 | 0.68 |
| 393.54 | 4.18 | 4.18 |
| 426.74 | 4.41 | 4.41 |
| 399.50 | 4.12 | 4.12 |
| 373.46 | 3.60 | 3.60 |
| 401.50 | 1.13 | 1.13 |
| 365.48 | 3.57 | 3.57 |
| 351.45 | 3.01 | 3.01 |
| 337.43 | 2.76 | 2.76 |
| 353.43 | 1.94 | 1.94 |
| 429.65 | 5.95 | 5.95 |
| 387.57 | 4.78 | 4.78 |
| 359.52 | 4.00 | 4.00 |
| 339.47 | 3.16 | 3.16 |
| 339.47 | 3.16 | 3.16 |
| 317.44 | 2.83 | 2.83 |
| 381.44 | 1.94 | 1.94 |
| 380.45 | 2.41 | 2.41 |
| 260.30 | -0.03 | -0.03 |
| 385.60 | 5.34 | 5.34 |
| 343.52 | 4.17 | 4.17 |
| 245.33 | 1.43 | 1.43 |
| 353.43 | 2.46 | 2.46 |
| 323.40 | 1.95 | 1.95 |
| 356.86 | 3.14 | 3.14 |
| 357.85 | 3.10 | 3.10 |
| 261.33 | 1.27 | 1.27 |
| 454.45 | 0.27 | 0.27 |