Basic Information
ID: ALA875135
Type: Binding
Description: The activity was examined against DNA topoisomerase I mediated DNA cleavage using 3''-End-labelled 161 BP plasmid DNA.+ indicates between 20 and 50% of the activity of 1 uM camptothecin
Activity Charts
Bioactivity
Activity Types for Assay ALA875135
Top1 cleavage activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 305.29 | 2.48 | 2.48 |
| 391.38 | 3.14 | 3.14 |
| 407.42 | 3.76 | 3.76 |
| 347.37 | 3.74 | 3.74 |