Assay Report Card

Basic Information

ID: ALA875796

Type: Binding

Description: Binding affinity to adenosine A1 receptor in rat brain membranes by measuring displacement of specific [3H]PIA as radioligand.

Tissue: Brain

Subcellular Fraction: Brain membranes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
267.25-1.98-1.98
266.26-1.38-1.38
268.701.341.34
370.410.090.09
301.760.420.42
508.321.071.07
301.69-1.33-1.33
384.40-0.20-0.20
371.400.360.36
510.290.410.41
251.25-1.56-1.56
251.25-0.95-0.95
266.26-1.37-1.37
357.370.050.05
282.26-2.28-2.28
388.43-0.29-0.29
347.33-0.36-0.36
346.33-2.75-2.75
285.24-1.84-1.84
308.30-1.84-1.84
285.69-0.30-0.30
281.27-1.59-1.59
251.25-1.56-1.56
317.76-0.61-0.61
317.76-0.61-0.61
300.70-0.72-0.72
282.26-1.16-1.16
398.420.190.19
307.31-1.23-1.23
338.37-0.77-0.77
401.38-0.35-0.35
374.36-0.60-0.60
284.700.310.31
303.68-0.35-0.35