Basic Information
ID: ALA882493
Type: Binding
Description: In vitro inhibition of ASBT mediated uptake of [14C]taurocholate (5 uM) in baby hamster cells expressing human IBAT
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA882493
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 473.68 | 5.41 | 5.41 |
| 545.81 | 5.48 | 5.48 |
| 633.92 | 5.52 | 5.52 |
| 600.91 | 7.29 | 7.29 |
| 646.93 | 6.15 | 6.15 |
| 501.69 | 5.19 | 5.19 |
| 473.68 | 4.89 | 4.89 |
| 550.77 | 6.37 | 6.37 |
| 579.83 | 6.29 | 6.29 |
| 678.93 | 4.10 | 4.10 |
| 500.75 | 5.46 | 5.46 |
| 458.67 | 4.98 | 4.98 |
| 558.83 | 6.12 | 6.12 |
| 573.76 | 4.01 | 4.01 |
| 479.63 | 5.68 | 5.68 |
| 503.71 | 5.42 | 5.42 |
| 535.75 | 6.54 | 6.54 |
| 475.65 | 4.81 | 4.81 |
| 491.67 | 5.55 | 5.55 |
| 565.80 | 5.80 | 5.80 |
| 517.69 | 4.86 | 4.86 |
| 515.78 | 5.61 | 5.61 |
| 550.79 | 5.97 | 5.97 |
| 626.93 | 5.70 | 5.70 |
| 642.93 | 4.94 | 4.94 |
| 686.98 | 4.96 | 4.96 |
| 612.90 | 5.31 | 5.31 |
| 640.95 | 6.09 | 6.09 |
| 674.97 | 6.62 | 6.62 |
| 641.90 | 7.31 | 7.31 |
| 535.77 | 5.74 | 5.74 |
| 535.77 | 5.74 | 5.74 |
| 537.74 | 4.79 | 4.79 |
| 443.65 | 5.40 | 5.40 |
| 493.71 | 6.55 | 6.55 |
| 459.65 | 5.11 | 5.11 |
| 523.74 | 6.56 | 6.56 |
| 489.75 | 6.12 | 6.12 |
| 499.76 | 6.70 | 6.70 |
| 509.71 | 6.26 | 6.26 |
| 449.68 | 5.46 | 5.46 |
| 501.69 | 5.19 | 5.19 |
| 487.66 | 5.10 | 5.10 |
| 449.68 | 5.46 | 5.46 |
| 444.64 | 4.79 | 4.79 |
| 473.68 | 4.89 | 4.89 |
| 528.80 | 6.24 | 6.24 |
| 444.64 | 4.79 | 4.79 |
| 444.64 | 4.79 | 4.79 |
| 459.65 | 5.11 | 5.11 |
| 473.68 | 5.41 | 5.41 |
| 459.68 | 4.22 | 4.22 |
| 530.78 | 5.34 | 5.34 |
| 559.77 | 6.03 | 6.03 |
| 574.74 | 3.98 | 3.98 |
| 660.87 | 5.42 | 5.42 |
| 694.89 | 5.95 | 5.95 |
| 695.88 | 5.34 | 5.34 |
| 515.78 | 5.61 | 5.61 |
| 709.88 | 7.83 | 7.83 |
| 709.88 | 7.83 | 7.83 |
| 711.85 | 6.67 | 6.67 |
| 755.90 | 6.69 | 6.69 |
| 667.79 | 6.65 | 6.65 |
| 637.77 | 6.78 | 6.78 |
| 722.87 | 7.38 | 7.38 |
| 834.20 | 5.84 | 5.84 |