Basic Information
ID: ALA884147
Type: Binding
Description: Percent inhibition of recombinant Plasmodium falciparum beta-Ketoacyl-acyl carrier protein synthase III activity (MBP-pfKASIII) expressed in E. coli cells using [1-14C]acetyl-CoA as radioligand upon incubation at 37 degrees C for 15 minutes with compound dissolved in 2% DMSO at 10 uM; NA = no activity
Organism: Plasmodium falciparum
Activity Charts
Bioactivity
Activity Types for Assay ALA884147
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.58 | 6.81 | 6.81 |
| 402.64 | 7.82 | 7.82 |
| 212.29 | 3.10 | 3.10 |
| 186.28 | 2.35 | 2.35 |
| 295.42 | 3.81 | 3.81 |
| 330.49 | 4.24 | 4.24 |
| 386.67 | ||
| 272.41 | 3.57 | 3.57 |
| 144.19 | 1.48 | 1.48 |
| 158.22 | 1.87 | 1.87 |
| 172.25 | 2.26 | 2.26 |
| 220.29 | 2.70 | 2.70 |
| 270.44 | 4.99 | 4.99 |
| 158.22 | 1.87 | 1.87 |
| 184.26 | 1.80 | 1.80 |
| 352.58 | 6.48 | 6.48 |
| 448.76 | 8.99 | 8.99 |