Basic Information
ID: ALA895598
Type: Functional
Description: Inhibition of MEK assessed as inhibition of ERK phosphorylation by Raf-MEK-ERK cascade assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA895598
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 478.66 | 5.04 | 5.04 |
| 452.17 | 3.11 | 3.11 |
| 392.12 | 3.55 | 3.55 |
| 436.17 | 3.17 | 3.17 |
| 285.28 | 1.35 | 1.35 |
| 416.19 | 3.05 | 3.05 |
| 388.14 | 2.57 | 2.57 |
| 447.20 | 1.53 | 1.53 |
| 387.15 | 1.97 | 1.97 |
| 401.18 | 2.23 | 2.23 |
| 415.21 | 2.57 | 2.57 |
| 431.21 | 1.59 | 1.59 |
| 445.23 | 1.98 | 1.98 |
| 373.12 | 1.96 | 1.96 |
| 401.18 | 2.45 | 2.45 |
| 415.21 | 2.84 | 2.84 |
| 475.26 | 2.10 | 2.10 |
| 440.22 | 2.74 | 2.74 |
| 417.18 | 1.43 | 1.43 |
| 431.20 | 1.82 | 1.82 |
| 431.16 | 1.52 | 1.52 |
| 413.19 | 2.62 | 2.62 |
| 447.20 | 0.79 | 0.79 |
| 275.28 | 1.68 | 1.68 |
| 340.15 | 2.13 | 2.13 |
| 386.18 | 1.67 | 1.67 |
| 479.27 | 4.29 | 4.29 |
| 293.33 | 2.38 | 2.38 |
| 312.16 | 2.53 | 2.53 |
| 307.35 | 2.09 | 2.09 |
| 289.31 | 1.93 | 1.93 |
| 286.27 | 1.24 | 1.24 |
| 319.34 | 1.29 | 1.29 |