Basic Information
ID: ALA897937
Type: Functional
Description: Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of LG-100268-induced transactivation
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA897937
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.57 | 6.89 | 6.89 |
| 467.61 | 7.03 | 7.03 |
| 509.69 | 8.20 | 8.20 |
| 543.71 | 8.60 | 8.60 |
| 509.65 | 7.33 | 7.33 |
| 523.68 | 7.72 | 7.72 |
| 523.68 | 7.58 | 7.58 |
| 563.74 | 8.50 | 8.50 |
| 615.82 | 9.14 | 9.14 |
| 557.69 | 8.24 | 8.24 |
| 575.68 | 8.38 | 8.38 |
| 625.69 | 9.26 | 9.26 |
| 571.72 | 8.17 | 8.17 |
| 589.71 | 8.30 | 8.30 |
| 603.74 | 8.69 | 8.69 |
| 617.77 | 9.08 | 9.08 |
| 583.73 | 8.64 | 8.64 |
| 510.64 | 6.74 | 6.74 |
| 524.67 | 7.13 | 7.13 |
| 538.69 | 7.52 | 7.52 |
| 552.72 | 7.91 | 7.91 |
| 586.74 | 8.31 | 8.31 |
| 531.68 | 6.36 | 6.36 |
| 545.71 | 6.75 | 6.75 |
| 559.73 | 7.14 | 7.14 |
| 573.76 | 7.53 | 7.53 |
| 573.76 | 7.53 | 7.53 |
| 587.79 | 7.92 | 7.92 |
| 587.79 | 7.92 | 7.92 |
| 601.81 | 8.31 | 8.31 |
| 607.78 | 7.93 | 7.93 |
| 619.79 | 8.40 | 8.40 |
| 593.75 | 7.79 | 7.79 |
| 611.74 | 7.92 | 7.92 |
| 611.74 | 7.92 | 7.92 |
| 611.74 | 7.92 | 7.92 |
| 625.77 | 8.31 | 8.31 |
| 639.79 | 8.70 | 8.70 |
| 607.78 | 8.09 | 8.09 |
| 623.78 | 7.79 | 7.79 |
| 661.75 | 8.80 | 8.80 |
| 661.75 | 8.80 | 8.80 |
| 661.75 | 8.80 | 8.80 |
| 675.77 | 9.19 | 9.19 |
| 689.80 | 9.58 | 9.58 |
| 729.74 | 9.82 | 9.82 |
| 643.81 | 8.94 | 8.94 |
| 669.85 | 9.45 | 9.45 |