Assay Report Card

Basic Information

ID: ALA899347

Type: Functional

Description: Antagonist activity at human recombinant NK1 receptor expressed in CHO cells assessed as inhibition of substance P-induced inositol phosphate generation by measuring remaining substance P response at 100 nM after 30 mins

Organism: Homo sapiens

Cell type: CHO

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
583.575.185.18
615.595.635.63
643.646.376.37
582.525.785.78
654.636.856.85
654.636.856.85
654.636.856.85
654.636.856.85
583.575.185.18