Basic Information
ID: ALA900188
Type: Functional
Description: Inhibition of transthyretin fibril formation at pH 4.4 at 100 uM
Activity Charts
Bioactivity
Activity Types for Assay ALA900188
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.49 | 4.01 | 4.01 |
| 336.48 | 3.46 | 3.46 |
| 359.43 | 3.51 | 3.51 |
| 382.29 | 5.10 | 5.10 |
| 343.43 | 3.81 | 3.81 |
| 356.25 | 4.74 | 4.74 |
| 274.35 | 1.92 | 1.92 |
| 194.22 | 1.73 | 1.73 |
| 291.52 | 3.02 | 3.02 |
| 194.22 | 2.10 | 2.10 |
| 284.34 | 3.56 | 3.56 |
| 223.18 | 2.13 | 2.13 |
| 223.18 | 2.13 | 2.13 |
| 233.25 | 2.55 | 2.55 |
| 239.64 | 2.64 | 2.64 |
| 432.35 | 6.66 | 6.66 |
| 283.35 | 3.71 | 3.71 |
| 314.35 | 1.35 | 1.35 |
| 305.36 | 3.82 | 3.82 |
| 475.47 | 6.07 | 6.07 |
| 322.80 | 5.01 | 5.01 |
| 292.36 | 2.77 | 2.77 |
| 312.78 | 3.11 | 3.11 |
| 292.38 | 4.00 | 4.00 |
| 308.38 | 3.23 | 3.23 |
| 322.45 | 5.02 | 5.02 |
| 342.44 | 5.03 | 5.03 |
| 354.33 | -0.26 | -0.26 |
| 331.39 | 3.94 | 3.94 |
| 359.27 | 3.79 | 3.79 |
| 330.43 | 4.18 | 4.18 |
| 332.43 | 3.68 | 3.68 |
| 310.42 | 2.88 | 2.88 |
| 319.74 | 2.57 | 2.57 |
| 379.80 | 4.10 | 4.10 |
| 418.88 | 5.12 | 5.12 |
| 434.84 | 4.42 | 4.42 |
| 389.84 | 4.51 | 4.51 |
| 320.39 | 3.80 | 3.80 |
| 384.82 | 3.94 | 3.94 |
| 317.81 | 3.53 | 3.53 |
| 410.93 | 6.04 | 6.04 |
| 354.86 | 4.93 | 4.93 |
| 394.88 | 5.56 | 5.56 |
| 270.33 | 1.99 | 1.99 |
| 335.24 | 3.94 | 3.94 |
| 330.32 | 3.33 | 3.33 |
| 350.23 | 5.06 | 5.06 |
| 387.05 | 5.64 | 5.64 |
| 255.29 | 1.19 | 1.19 |
| 223.30 | 1.78 | 1.78 |
| 189.28 | 1.29 | 1.29 |
| 210.26 | 0.87 | 0.87 |
| 278.16 | 2.78 | 2.78 |
| 278.16 | 2.78 | 2.78 |
| 225.27 | 1.18 | 1.18 |
| 269.32 | 1.49 | 1.49 |
| 261.70 | 2.27 | 2.27 |
| 254.27 | 1.38 | 1.38 |
| 267.74 | 2.31 | 2.31 |
| 324.19 | 4.40 | 4.40 |
| 243.72 | 2.13 | 2.13 |
| 374.30 | 6.42 | 6.42 |
| 336.78 | 4.50 | 4.50 |
| 374.30 | 6.42 | 6.42 |
| 422.81 | 4.33 | 4.33 |
| 253.71 | 1.27 | 1.27 |
| 393.90 | 5.41 | 5.41 |
| 366.32 | 6.11 | 6.11 |
| 318.36 | 4.59 | 4.59 |
| 329.40 | 5.07 | 5.07 |
| 252.66 | 2.59 | 2.59 |
| 370.43 | 3.25 | 3.25 |
| 408.41 | 3.54 | 3.54 |
| 291.36 | 1.95 | 1.95 |
| 318.38 | 2.33 | 2.33 |
| 336.83 | 3.28 | 3.28 |
| 405.59 | 3.68 | 3.68 |
| 375.54 | 4.22 | 4.22 |
| 400.55 | 3.01 | 3.01 |
| 417.64 | 5.22 | 5.22 |
| 347.55 | 4.07 | 4.07 |
| 388.51 | 3.14 | 3.14 |
| 441.59 | 5.84 | 5.84 |
| 358.85 | 4.09 | 4.09 |
| 373.38 | 3.17 | 3.17 |
| 389.84 | 3.68 | 3.68 |
| 224.24 | 1.82 | 1.82 |
| 332.34 | 4.00 | 4.00 |
| 270.31 | -0.28 | -0.28 |
| 306.84 | 4.52 | 4.52 |
| 276.77 | 3.50 | 3.50 |
| 345.19 | 4.69 | 4.69 |
| 317.35 | 3.64 | 3.64 |
| 331.45 | 2.80 | 2.80 |
| 347.81 | 5.40 | 5.40 |
| 358.68 | 5.43 | 5.43 |