Basic Information
ID: ALA904746
Type: Binding
Description: Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidation
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA904746
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 222.37 | 3.47 | 3.47 |
| 236.40 | 3.86 | 3.86 |
| 250.43 | 4.25 | 4.25 |
| 248.41 | 4.02 | 4.02 |
| 248.41 | 4.02 | 4.02 |
| 264.45 | 4.64 | 4.64 |
| 236.35 | 3.56 | 3.56 |
| 264.41 | 4.34 | 4.34 |
| 262.39 | 4.12 | 4.12 |
| 262.39 | 4.12 | 4.12 |
| 278.44 | 4.73 | 4.73 |
| 300.38 | 4.04 | 4.04 |
| 298.36 | 4.17 | 4.17 |
| 314.41 | 4.43 | 4.43 |
| 312.39 | 4.56 | 4.56 |
| 280.41 | 3.31 | 3.31 |
| 280.41 | 3.31 | 3.31 |
| 308.46 | 3.79 | 3.79 |
| 308.46 | 3.79 | 3.79 |
| 316.38 | 3.01 | 3.01 |
| 316.38 | 3.01 | 3.01 |
| 372.49 | 5.10 | 5.10 |
| 372.49 | 5.10 | 5.10 |
| 330.40 | 3.40 | 3.40 |
| 330.40 | 3.40 | 3.40 |
| 358.46 | 4.71 | 4.71 |
| 358.46 | 4.71 | 4.71 |
| 386.51 | 5.49 | 5.49 |
| 386.51 | 5.49 | 5.49 |
| 266.42 | 3.22 | 3.22 |
| 266.42 | 3.22 | 3.22 |
| 270.84 | 4.07 | 4.07 |
| 270.84 | 4.07 | 4.07 |
| 236.40 | 3.86 | 3.86 |
| 236.40 | 3.86 | 3.86 |
| 250.43 | 4.25 | 4.25 |
| 250.43 | 4.25 | 4.25 |
| 248.41 | 4.02 | 4.02 |
| 248.41 | 4.02 | 4.02 |
| 262.44 | 4.41 | 4.41 |
| 262.44 | 4.41 | 4.41 |
| 264.45 | 4.49 | 4.49 |
| 264.45 | 4.49 | 4.49 |
| 278.48 | 4.88 | 4.88 |
| 298.47 | 5.21 | 5.21 |
| 298.47 | 5.21 | 5.21 |
| 299.93 | 4.43 | 4.43 |
| 278.48 | 4.88 | 4.88 |