Basic Information
ID: ALA905756
Type: Binding
Description: Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNL assessed as remaining 5-LO activity at 1 uM
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA905756
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 204.25 | 2.40 | 2.40 |
| 218.28 | 2.70 | 2.70 |
| 248.31 | 2.71 | 2.71 |
| 372.53 | 4.93 | 4.93 |
| 500.62 | 4.67 | 4.67 |
| 454.55 | 4.38 | 4.38 |
| 454.59 | 4.59 | 4.59 |
| 440.57 | 4.66 | 4.66 |
| 402.56 | 4.53 | 4.53 |
| 432.57 | 3.81 | 3.81 |
| 439.58 | 4.72 | 4.72 |
| 471.65 | 5.76 | 5.76 |
| 461.53 | 5.32 | 5.32 |
| 338.45 | 4.09 | 4.09 |
| 357.52 | 4.43 | 4.43 |
| 317.47 | 3.97 | 3.97 |
| 341.45 | 3.96 | 3.96 |
| 395.55 | 4.02 | 4.02 |
| 443.61 | 3.85 | 3.85 |
| 401.58 | 4.08 | 4.08 |
| 344.48 | 4.15 | 4.15 |
| 373.54 | 4.13 | 4.13 |
| 235.27 | 1.80 | 1.80 |
| 262.29 | 2.43 | 2.43 |
| 262.29 | 2.43 | 2.43 |
| 249.25 | 1.52 | 1.52 |
| 261.35 | 2.77 | 2.77 |
| 261.35 | 2.77 | 2.77 |
| 248.31 | 1.86 | 1.86 |
| 263.32 | 3.10 | 3.10 |
| 263.32 | 3.10 | 3.10 |
| 250.28 | 2.19 | 2.19 |
| 218.28 | 2.70 | 2.70 |
| 205.24 | 1.79 | 1.79 |
| 232.31 | 2.63 | 2.63 |
| 232.31 | 2.63 | 2.63 |
| 219.27 | 1.72 | 1.72 |
| 262.33 | 2.64 | 2.64 |
| 262.33 | 2.64 | 2.64 |
| 249.29 | 1.73 | 1.73 |
| 308.36 | 2.73 | 2.73 |
| 308.36 | 2.73 | 2.73 |
| 295.32 | 1.82 | 1.82 |
| 313.38 | 3.44 | 3.44 |
| 304.37 | 3.12 | 3.12 |
| 304.37 | 3.12 | 3.12 |
| 291.33 | 2.21 | 2.21 |
| 234.28 | 2.40 | 2.40 |
| 218.28 | 2.32 | 2.32 |
| 248.31 | 2.33 | 2.33 |
| 247.32 | 2.46 | 2.46 |
| 294.33 | 2.42 | 2.42 |
| 385.57 | 5.21 | 5.21 |
| 366.51 | 4.87 | 4.87 |
| 386.56 | 5.24 | 5.24 |
| 386.56 | 5.24 | 5.24 |
| 246.31 | 2.42 | 2.42 |