Basic Information
ID: ALA908289
Type: Functional
Description: Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assay
Organism: Homo sapiens
Cell type: IMR-32
Activity Charts
Bioactivity
Activity Types for Assay ALA908289
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.33 | 4.22 | 4.22 |
| 436.46 | 2.92 | 2.92 |
| 424.43 | 3.06 | 3.06 |
| 431.45 | 2.79 | 2.79 |
| 454.91 | 3.88 | 3.88 |
| 438.46 | 3.10 | 3.10 |
| 437.47 | 3.28 | 3.28 |
| 450.49 | 3.93 | 3.93 |
| 458.87 | 3.71 | 3.71 |
| 440.47 | 3.34 | 3.34 |
| 436.46 | 2.92 | 2.92 |
| 474.44 | 3.93 | 3.93 |
| 454.45 | 3.06 | 3.06 |
| 440.88 | 3.57 | 3.57 |
| 410.45 | 3.34 | 3.34 |
| 422.44 | 2.53 | 2.53 |
| 442.42 | 3.19 | 3.19 |
| 410.45 | 3.34 | 3.34 |
| 450.49 | 3.31 | 3.31 |
| 474.44 | 3.93 | 3.93 |
| 442.42 | 3.19 | 3.19 |
| 485.33 | 3.68 | 3.68 |
| 398.41 | 3.47 | 3.47 |
| 436.46 | 2.78 | 2.78 |
| 398.41 | 3.47 | 3.47 |
| 422.44 | 2.62 | 2.62 |
| 420.47 | 3.22 | 3.22 |
| 460.41 | 3.33 | 3.33 |
| 490.43 | 3.81 | 3.81 |
| 398.41 | 3.47 | 3.47 |
| 472.44 | 3.52 | 3.52 |
| 380.42 | 3.33 | 3.33 |
| 428.44 | 3.47 | 3.47 |
| 434.49 | 3.48 | 3.48 |
| 424.43 | 3.06 | 3.06 |
| 424.43 | 3.06 | 3.06 |
| 406.44 | 2.92 | 2.92 |
| 428.44 | 3.47 | 3.47 |
| 485.33 | 3.68 | 3.68 |
| 460.41 | 3.65 | 3.65 |
| 422.46 | 3.53 | 3.53 |
| 440.88 | 3.57 | 3.57 |
| 440.88 | 3.57 | 3.57 |
| 458.87 | 3.71 | 3.71 |
| 422.44 | 2.49 | 2.49 |
| 475.33 | 4.22 | 4.22 |