ID: ALA908865
Type: Functional
Description: Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay
Organism: Homo sapiens
Cell type: HEK293
Bioactivity
Activity Types for Assay ALA908865
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
341.37 | 2.02 | 2.02 |
352.35 | 1.65 | 1.65 |
429.27 | 3.81 | 3.81 |
431.24 | 3.34 | 3.34 |
302.29 | 0.95 | 0.95 |
435.66 | 3.98 | 3.98 |
180.16 | 0.96 | 0.96 |
259.06 | 1.73 | 1.73 |
273.08 | 2.12 | 2.12 |
480.11 | 4.09 | 4.09 |
335.15 | 3.14 | 3.14 |
480.11 | 4.09 | 4.09 |
326.10 | 2.13 | 2.13 |
287.15 | 3.21 | 3.21 |
480.11 | 4.09 | 4.09 |
261.07 | 1.40 | 1.40 |
322.32 | 2.57 | 2.57 |
340.31 | 2.71 | 2.71 |
356.76 | 3.22 | 3.22 |
401.22 | 3.33 | 3.33 |
336.35 | 2.88 | 2.88 |
352.35 | 2.58 | 2.58 |
400.23 | 3.91 | 3.91 |
350.17 | 2.75 | 2.75 |
367.32 | 2.47 | 2.47 |
397.21 | 2.99 | 2.99 |
398.42 | 4.23 | 4.23 |
428.25 | 3.21 | 3.21 |
432.86 | 4.89 | 4.89 |
379.38 | 2.46 | 2.46 |
434.40 | 4.51 | 4.51 |