Basic Information
ID: ALA908896
Type: Functional
Description: Ability to open human urinary bladder Kir6.2 containing SUR2B in Ltk cells by FLIPR assay relative to P1075
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Ltk
Target: Sulfonylurea receptor 2, Kir6.2(ALA2095198)
Document: ALA1137338
Ability to open human urinary bladder Kir6.2 containing SUR2B in Ltk cells by FLIPR assay relative to P1075: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA908896
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 286.33 | 1.75 | 1.75 |
| 231.30 | 2.11 | 2.11 |
| 337.30 | 3.17 | 3.17 |
| 394.20 | 2.82 | 2.82 |
| 394.20 | 3.17 | 3.17 |
| 408.22 | 3.56 | 3.56 |
| 408.22 | 3.56 | 3.56 |
| 422.25 | 3.95 | 3.95 |
| 436.28 | 4.19 | 4.19 |
| 469.25 | 3.79 | 3.79 |
| 418.29 | 4.12 | 4.12 |
| 409.26 | 1.97 | 1.97 |
| 422.25 | 3.60 | 3.60 |
| 394.25 | 4.01 | 4.01 |
| 438.71 | 4.12 | 4.12 |
| 394.20 | 3.17 | 3.17 |
| 422.25 | 3.95 | 3.95 |
| 394.25 | 4.35 | 4.35 |
| 407.24 | 3.08 | 3.08 |
| 483.16 | 4.22 | 4.22 |
| 394.20 | 3.17 | 3.17 |
| 438.71 | 4.12 | 4.12 |
| 394.20 | 3.17 | 3.17 |
| 424.22 | 2.79 | 2.79 |
| 456.27 | 4.52 | 4.52 |
| 438.71 | 4.46 | 4.46 |
| 406.25 | 4.71 | 4.71 |
| 406.25 | 4.22 | 4.22 |
| 408.22 | 3.56 | 3.56 |
| 424.22 | 2.79 | 2.79 |
| 436.28 | 4.34 | 4.34 |
| 406.25 | 4.71 | 4.71 |
| 408.27 | 3.95 | 3.95 |
| 436.28 | 4.34 | 4.34 |
| 394.20 | 3.52 | 3.52 |
| 408.22 | 3.56 | 3.56 |
| 436.28 | 4.34 | 4.34 |
| 438.71 | 4.46 | 4.46 |
| 394.20 | 3.52 | 3.52 |
| 422.25 | 3.60 | 3.60 |
| 408.22 | 3.56 | 3.56 |
| 408.22 | 3.56 | 3.56 |
| 436.28 | 4.34 | 4.34 |
| 408.22 | 3.91 | 3.91 |
| 450.30 | 4.38 | 4.38 |
| 408.22 | 3.91 | 3.91 |
| 377.80 | 3.49 | 3.49 |
| 436.28 | 4.34 | 4.34 |
| 483.16 | 4.57 | 4.57 |
| 424.29 | 4.27 | 4.27 |
| 450.30 | 4.38 | 4.38 |
| 408.22 | 3.56 | 3.56 |
| 408.22 | 3.56 | 3.56 |
| 436.28 | 4.34 | 4.34 |
| 377.80 | 3.84 | 3.84 |
| 424.29 | 4.27 | 4.27 |
| 422.25 | 3.60 | 3.60 |
| 394.20 | 3.17 | 3.17 |
| 469.25 | 3.44 | 3.44 |
| 380.17 | 2.78 | 2.78 |
| 394.20 | 3.17 | 3.17 |
| 408.22 | 3.56 | 3.56 |
| 436.28 | 4.19 | 4.19 |
| 418.29 | 3.77 | 3.77 |
| 325.41 | 3.31 | 3.31 |
| 380.17 | 1.94 | 1.94 |
| 414.25 | 2.50 | 2.50 |
| 414.25 | 2.50 | 2.50 |
| 428.28 | 2.89 | 2.89 |
| 428.28 | 2.89 | 2.89 |
| 412.28 | 3.31 | 3.31 |