Basic Information
ID: ALA909298
Type: Functional
Description: Antagonist activity assessed as inhibition of loperamide-stimulated [35S]GTPgammaS binding to human mu opioid receptor expressed in CHO cells
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA909298
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.38 | 1.30 | 1.30 |
| 341.41 | 1.53 | 1.53 |
| 309.45 | 4.23 | 4.23 |
| 350.51 | 3.57 | 3.57 |
| 342.53 | 3.91 | 3.91 |
| 393.58 | 3.94 | 3.94 |
| 408.54 | 3.66 | 3.66 |
| 302.46 | 2.99 | 2.99 |
| 274.41 | 2.31 | 2.31 |
| 302.42 | 2.22 | 2.22 |
| 442.60 | 5.67 | 5.67 |
| 456.63 | 5.46 | 5.46 |
| 364.49 | 3.52 | 3.52 |
| 378.52 | 3.45 | 3.45 |
| 400.57 | 5.03 | 5.03 |
| 400.57 | 5.03 | 5.03 |
| 392.54 | 3.84 | 3.84 |
| 336.48 | 3.88 | 3.88 |
| 401.55 | 4.42 | 4.42 |
| 351.49 | 3.27 | 3.27 |
| 350.51 | 3.88 | 3.88 |
| 364.53 | 3.92 | 3.92 |
| 351.49 | 3.27 | 3.27 |
| 351.49 | 3.27 | 3.27 |
| 378.56 | 4.31 | 4.31 |
| 364.53 | 4.27 | 4.27 |
| 340.47 | 3.47 | 3.47 |
| 340.47 | 3.47 | 3.47 |
| 338.47 | 1.64 | 1.64 |
| 400.54 | 3.06 | 3.06 |
| 356.54 | 3.94 | 3.94 |
| 356.54 | 3.94 | 3.94 |
| 379.50 | 3.91 | 3.91 |
| 364.53 | 4.18 | 4.18 |
| 356.55 | 4.26 | 4.26 |
| 364.53 | 4.18 | 4.18 |
| 364.53 | 4.18 | 4.18 |
| 384.95 | 4.53 | 4.53 |
| 384.95 | 4.53 | 4.53 |
| 426.60 | 5.62 | 5.62 |
| 384.95 | 4.53 | 4.53 |
| 366.51 | 3.58 | 3.58 |
| 335.49 | 4.94 | 4.94 |
| 336.48 | 3.70 | 3.70 |
| 410.61 | 5.91 | 5.91 |
| 468.64 | 5.70 | 5.70 |
| 366.51 | 3.58 | 3.58 |
| 366.51 | 3.58 | 3.58 |
| 378.52 | 3.96 | 3.96 |
| 350.51 | 4.05 | 4.05 |
| 454.61 | 5.61 | 5.61 |
| 453.63 | 5.01 | 5.01 |
| 363.51 | 3.10 | 3.10 |
| 336.48 | 3.70 | 3.70 |
| 260.38 | 1.96 | 1.96 |
| 350.51 | 3.57 | 3.57 |