Basic Information
ID: ALA914283
Type: Functional
Description: Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium concentration
Organism: Rattus norvegicus
Strain: Wistar
Activity Charts
Bioactivity
Activity Types for Assay ALA914283
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.42 | 2.80 | 2.80 |
| 339.48 | 4.02 | 4.02 |
| 321.42 | 3.89 | 3.89 |
| 348.45 | 4.36 | 4.36 |
| 350.42 | 3.80 | 3.80 |
| 334.42 | 3.97 | 3.97 |
| 334.42 | 3.97 | 3.97 |
| 334.42 | 3.97 | 3.97 |
| 350.42 | 3.67 | 3.67 |
| 350.42 | 3.69 | 3.69 |
| 320.39 | 3.89 | 3.89 |
| 350.42 | 3.67 | 3.67 |
| 334.42 | 3.97 | 3.97 |
| 402.49 | 3.32 | 3.32 |
| 398.53 | 3.39 | 3.39 |
| 505.62 | 2.40 | 2.40 |
| 376.42 | 3.09 | 3.09 |
| 333.43 | 3.85 | 3.85 |
| 370.47 | 3.52 | 3.52 |
| 433.42 | 2.53 | 2.53 |
| 369.40 | 3.21 | 3.21 |
| 333.43 | 3.85 | 3.85 |
| 364.44 | 3.98 | 3.98 |
| 364.45 | 3.98 | 3.98 |
| 365.43 | 3.38 | 3.38 |
| 381.43 | 3.08 | 3.08 |
| 364.45 | 4.12 | 4.12 |
| 367.40 | 2.97 | 2.97 |
| 387.82 | 3.31 | 3.31 |
| 371.37 | 2.80 | 2.80 |
| 423.56 | 5.87 | 5.87 |
| 411.53 | 3.63 | 3.63 |
| 411.53 | 3.63 | 3.63 |
| 336.39 | 3.56 | 3.56 |
| 411.53 | 3.63 | 3.63 |
| 375.43 | 3.70 | 3.70 |
| 358.44 | 4.14 | 4.14 |
| 358.44 | 4.14 | 4.14 |
| 348.40 | 3.61 | 3.61 |
| 350.42 | 3.46 | 3.46 |
| 335.41 | 3.59 | 3.59 |
| 358.44 | 4.14 | 4.14 |
| 352.41 | 4.11 | 4.11 |
| 348.45 | 4.28 | 4.28 |
| 364.45 | 3.98 | 3.98 |
| 352.41 | 4.11 | 4.11 |
| 333.43 | 3.85 | 3.85 |
| 333.43 | 4.15 | 4.15 |
| 348.45 | 3.98 | 3.98 |
| 335.40 | 4.23 | 4.23 |
| 320.44 | 4.33 | 4.33 |
| 352.46 | 4.10 | 4.10 |
| 351.47 | 4.70 | 4.70 |
| 335.40 | 4.23 | 4.23 |
| 351.41 | 3.07 | 3.07 |
| 351.41 | 3.07 | 3.07 |
| 349.44 | 2.82 | 2.82 |