Basic Information
ID: ALA914418
Type: Binding
Description: Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay
Organism: Homo sapiens
Cell type: MDR
Activity Charts
Bioactivity
Activity Types for Assay ALA914418
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.45 | 3.24 | 3.24 |
| 327.42 | 3.00 | 3.00 |
| 277.36 | 2.11 | 2.11 |
| 458.60 | 4.37 | 4.37 |
| 462.57 | 4.20 | 4.20 |
| 369.46 | 2.57 | 2.57 |
| 355.48 | 3.58 | 3.58 |
| 355.48 | 3.58 | 3.58 |
| 367.49 | 3.73 | 3.73 |
| 383.53 | 4.36 | 4.36 |
| 474.60 | 4.07 | 4.07 |
| 247.34 | 3.03 | 3.03 |
| 293.36 | 1.35 | 1.35 |
| 372.44 | 2.59 | 2.59 |
| 327.42 | 2.80 | 2.80 |
| 456.59 | 5.08 | 5.08 |
| 367.49 | 3.73 | 3.73 |
| 383.53 | 4.36 | 4.36 |
| 462.57 | 4.20 | 4.20 |
| 464.58 | 4.05 | 4.05 |
| 459.59 | 4.23 | 4.23 |
| 369.51 | 3.58 | 3.58 |
| 385.50 | 3.08 | 3.08 |
| 279.34 | 0.96 | 0.96 |
| 372.44 | 2.59 | 2.59 |
| 431.53 | 3.64 | 3.64 |
| 434.51 | 3.62 | 3.62 |
| 383.49 | 3.00 | 3.00 |
| 291.39 | 2.50 | 2.50 |
| 369.46 | 2.57 | 2.57 |
| 447.58 | 4.82 | 4.82 |
| 383.49 | 3.43 | 3.43 |
| 357.45 | 2.95 | 2.95 |
| 564.73 | 5.64 | 5.64 |
| 493.65 | 6.05 | 6.05 |
| 458.60 | 4.06 | 4.06 |
| 277.36 | 2.11 | 2.11 |
| 385.55 | 4.21 | 4.21 |
| 417.55 | 4.88 | 4.88 |
| 474.60 | 4.07 | 4.07 |
| 369.46 | 2.61 | 2.61 |
| 399.58 | 4.87 | 4.87 |
| 478.61 | 4.71 | 4.71 |
| 383.53 | 4.23 | 4.23 |
| 371.48 | 2.42 | 2.42 |
| 474.60 | 4.07 | 4.07 |
| 433.50 | 4.14 | 4.14 |
| 381.52 | 4.16 | 4.16 |
| 375.47 | 4.35 | 4.35 |
| 444.58 | 4.06 | 4.06 |
| 473.61 | 5.31 | 5.31 |
| 277.36 | 2.11 | 2.11 |
| 509.65 | 5.38 | 5.38 |
| 462.57 | 4.20 | 4.20 |
| 367.49 | 3.73 | 3.73 |
| 419.52 | 3.73 | 3.73 |
| 433.59 | 5.51 | 5.51 |
| 399.53 | 4.07 | 4.07 |
| 479.62 | 5.66 | 5.66 |
| 543.71 | 7.21 | 7.21 |
| 279.34 | 0.96 | 0.96 |
| 372.44 | 2.59 | 2.59 |
| 336.24 | 3.64 | 3.64 |
| 387.44 | 4.42 | 4.42 |
| 387.48 | 4.92 | 4.92 |
| 532.73 | 8.15 | 8.15 |
| 422.48 | 6.26 | 6.26 |
| 386.50 | 5.98 | 5.98 |
| 380.56 | 5.36 | 5.36 |
| 400.48 | 5.48 | 5.48 |
| 303.35 | 1.55 | 1.55 |
| 371.44 | 3.67 | 3.67 |
| 400.52 | 6.05 | 6.05 |
| 516.73 | 8.27 | 8.27 |
| 373.50 | 3.58 | 3.58 |
| 434.54 | 6.60 | 6.60 |
| 374.14 | -0.17 | -0.17 |
| 390.91 | 6.62 | 6.62 |
| 295.31 | 0.91 | 0.91 |
| 398.55 | 7.09 | 7.09 |
| 212.25 | 0.60 | 0.60 |
| 367.62 | 3.54 | 3.54 |
| 293.32 | 0.77 | 0.77 |
| 325.77 | 2.33 | 2.33 |
| 209.24 | 1.46 | 1.46 |
| 472.63 | 4.68 | 4.68 |
| 501.67 | 4.44 | 4.44 |
| 279.34 | 0.96 | 0.96 |
| 488.68 | 7.29 | 7.29 |
| 510.68 | 8.12 | 8.12 |
| 482.67 | 8.29 | 8.29 |
| 488.72 | 8.44 | 8.44 |
| 445.56 | 4.79 | 4.79 |
| 382.50 | 3.07 | 3.07 |
| 424.54 | 3.27 | 3.27 |
| 407.60 | 6.32 | 6.32 |
| 421.63 | 6.71 | 6.71 |
| 368.48 | 2.76 | 2.76 |
| 382.50 | 3.07 | 3.07 |
| 511.71 | 6.98 | 6.98 |
| 437.37 | 4.07 | 4.07 |
| 531.70 | 4.45 | 4.45 |
| 472.59 | 3.70 | 3.70 |
| 403.52 | 4.44 | 4.44 |
| 458.60 | 4.37 | 4.37 |
| 333.48 | 5.25 | 5.25 |
| 631.82 | 9.12 | 9.12 |
| 493.65 | 6.05 | 6.05 |
| 472.63 | 4.68 | 4.68 |
| 323.44 | 4.25 | 4.25 |
| 323.44 | 4.25 | 4.25 |
| 431.58 | 5.23 | 5.23 |
| 471.64 | 6.15 | 6.15 |
| 369.46 | 2.57 | 2.57 |
| 493.65 | 6.05 | 6.05 |
| 457.61 | 5.20 | 5.20 |
| 527.49 | 5.68 | 5.68 |
| 291.39 | 2.42 | 2.42 |
| 411.59 | 5.01 | 5.01 |
| 303.40 | 2.29 | 2.29 |
| 445.60 | 5.62 | 5.62 |
| 367.49 | 3.58 | 3.58 |
| 289.38 | 2.04 | 2.04 |
| 379.50 | 3.51 | 3.51 |
| 493.05 | 5.03 | 5.03 |
| 379.50 | 3.51 | 3.51 |
| 484.64 | 4.46 | 4.46 |
| 472.63 | 4.68 | 4.68 |
| 488.63 | 4.38 | 4.38 |
| 245.32 | 2.51 | 2.51 |
| 312.37 | 3.44 | 3.44 |
| 284.31 | 2.97 | 2.97 |
| 409.53 | 4.30 | 4.30 |
| 382.50 | 3.07 | 3.07 |
| 368.48 | 2.76 | 2.76 |
| 493.05 | 5.03 | 5.03 |
| 488.63 | 4.38 | 4.38 |
| 380.49 | 3.28 | 3.28 |
| 335.45 | 4.18 | 4.18 |
| 245.32 | 2.56 | 2.56 |
| 351.49 | 4.76 | 4.76 |
| 472.63 | 4.68 | 4.68 |
| 443.47 | 5.37 | 5.37 |
| 321.46 | 4.65 | 4.65 |
| 231.34 | 3.04 | 3.04 |
| 368.48 | 2.76 | 2.76 |
| 337.46 | 4.37 | 4.37 |
| 365.52 | 5.15 | 5.15 |
| 420.47 | 4.26 | 4.26 |
| 445.56 | 4.68 | 4.68 |
| 382.50 | 3.07 | 3.07 |
| 472.63 | 4.68 | 4.68 |
| 379.54 | 5.54 | 5.54 |
| 393.57 | 5.93 | 5.93 |
| 367.49 | 3.99 | 3.99 |
| 460.59 | 5.62 | 5.62 |
| 488.63 | 4.38 | 4.38 |
| 398.50 | 2.77 | 2.77 |
| 309.80 | 4.55 | 4.55 |