Basic Information
ID: ALA915475
Type: Binding
Description: Inhibition of BCRP expressed in mitoxantrone-resistant human HCT116 cells assessed as increase in mitoxantrone accumulation at 10 uM after 15 mins
Organism: Homo sapiens
Cell type: HCT-116
Activity Charts
Bioactivity
Activity Types for Assay ALA915475
Fluorescence intensity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 493.62 | 4.59 | 4.59 |
| 316.31 | 0.80 | 0.80 |
| 302.33 | 1.28 | 1.28 |
| 374.39 | 2.19 | 2.19 |
| 274.28 | 0.54 | 0.54 |
| 316.36 | 1.67 | 1.67 |
| 330.38 | 2.06 | 2.06 |
| 330.38 | 1.91 | 1.91 |
| 344.41 | 2.45 | 2.45 |
| 318.33 | 0.25 | 0.25 |
| 370.45 | 2.84 | 2.84 |
| 309.32 | 2.47 | 2.47 |
| 339.35 | 2.48 | 2.48 |
| 369.37 | 2.49 | 2.49 |
| 355.35 | 2.45 | 2.45 |
| 379.46 | 2.94 | 2.94 |