Basic Information
ID: ALA917720
Type: Functional
Description: Inhibition of BACE1 in HEK293 cells assessed as decrease in production of N-terminal fragment of sAPP
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA917720
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 596.73 | 3.17 | 3.17 |
| 612.77 | 3.80 | 3.80 |
| 606.79 | 3.81 | 3.81 |
| 607.78 | 2.87 | 2.87 |
| 578.74 | 3.03 | 3.03 |
| 582.70 | 3.14 | 3.14 |
| 556.66 | 2.37 | 2.37 |
| 584.71 | 3.02 | 3.02 |