Basic Information
ID: ALA918058
Type: ADME
Description: Cytotoxicity against mouse L1210/0 cells after 48 hrs
Organism: Mus musculus
Cell type: L1210/0
Activity Charts
Bioactivity
Activity Types for Assay ALA918058
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 273.19 | -0.44 | -0.44 |
| 204.16 | -1.36 | -1.36 |
| 200.19 | -1.19 | -1.19 |
| 185.18 | -1.21 | -1.21 |
| 186.17 | -1.50 | -1.50 |
| 265.06 | -0.73 | -0.73 |
| 312.06 | -0.89 | -0.89 |
| 243.65 | 0.03 | 0.03 |
| 333.14 | -0.46 | -0.46 |
| 354.10 | -1.22 | -1.22 |
| 291.10 | -0.13 | -0.13 |
| 185.18 | -1.21 | -1.21 |
| 243.22 | -2.56 | -2.56 |
| 231.16 | -1.59 | -1.59 |
| 270.68 | 1.02 | 1.02 |
| 237.26 | -0.14 | -0.14 |
| 210.19 | -0.50 | -0.50 |
| 230.18 | -1.30 | -1.30 |
| 285.69 | 0.60 | 0.60 |
| 305.12 | 1.67 | 1.67 |
| 264.25 | -0.48 | -0.48 |
| 264.25 | -0.48 | -0.48 |
| 430.74 | 2.41 | 2.41 |
| 322.71 | 1.42 | 1.42 |
| 340.72 | 0.62 | 0.62 |
| 321.29 | -0.45 | -0.45 |
| 246.19 | -1.68 | -1.68 |
| 288.20 | -0.86 | -0.86 |
| 265.23 | -1.77 | -1.77 |
| 256.26 | 2.09 | 2.09 |
| 272.26 | 1.79 | 1.79 |
| 474.90 | 4.57 | 4.57 |
| 558.33 | 3.23 | 3.23 |
| 500.43 | 3.64 | 3.64 |
| 466.88 | 3.28 | 3.28 |
| 511.33 | 3.39 | 3.39 |
| 474.90 | 4.57 | 4.57 |
| 432.43 | 2.62 | 2.62 |
| 450.42 | 2.76 | 2.76 |
| 284.36 | -1.13 | -1.13 |
| 296.20 | -0.80 | -0.80 |
| 256.26 | -1.26 | -1.26 |
| 258.23 | -2.54 | -2.54 |
| 220.61 | -0.84 | -0.84 |
| 270.17 | -0.56 | -0.56 |
| 468.44 | 1.61 | 1.61 |
| 518.44 | 2.49 | 2.49 |
| 450.45 | 1.47 | 1.47 |
| 320.18 | 0.32 | 0.32 |
| 252.18 | -0.70 | -0.70 |
| 211.20 | -0.07 | -0.07 |
| 273.20 | -1.91 | -1.91 |
| 256.21 | -2.01 | -2.01 |
| 253.21 | -1.95 | -1.95 |
| 225.21 | -1.33 | -1.33 |
| 130.08 | -0.80 | -0.80 |
| 503.61 | 5.18 | 5.18 |
| 323.83 | 2.50 | 2.50 |
| 324.82 | 1.89 | 1.89 |
| 282.74 | 0.87 | 0.87 |
| 295.77 | 2.03 | 2.03 |
| 281.32 | 1.63 | 1.63 |
| 282.30 | 1.75 | 1.75 |
| 296.33 | 2.06 | 2.06 |
| 300.75 | 2.70 | 2.70 |
| 342.40 | 3.71 | 3.71 |
| 372.43 | 3.72 | 3.72 |
| 337.17 | 1.52 | 1.52 |
| 468.95 | 4.87 | 4.87 |
| 489.58 | 4.79 | 4.79 |
| 305.38 | 1.55 | 1.55 |
| 304.40 | 1.43 | 1.43 |
| 305.39 | 0.82 | 0.82 |
| 386.46 | 3.77 | 3.77 |
| 308.81 | 2.91 | 2.91 |
| 269.24 | -1.00 | -1.00 |
| 261.24 | -1.34 | -1.34 |
| 266.34 | 0.97 | 0.97 |
| 295.30 | -1.72 | -1.72 |
| 294.32 | -1.43 | -1.43 |
| 356.43 | 3.76 | 3.76 |
| 370.46 | 4.07 | 4.07 |
| 328.27 | 0.13 | 0.13 |
| 289.19 | -1.15 | -1.15 |
| 266.73 | 1.89 | 1.89 |
| 282.74 | 1.18 | 1.18 |
| 390.87 | 4.41 | 4.41 |
| 294.32 | -1.43 | -1.43 |
| 252.71 | 1.81 | 1.81 |
| 335.41 | 2.66 | 2.66 |
| 413.35 | 0.80 | 0.80 |
| 472.51 | 2.15 | 2.15 |
| 378.28 | -0.62 | -0.62 |
| 254.24 | -1.18 | -1.18 |
| 337.43 | 2.91 | 2.91 |
| 289.38 | 1.84 | 1.84 |
| 224.26 | -0.05 | -0.05 |
| 392.24 | 1.58 | 1.58 |
| 266.34 | 0.97 | 0.97 |
| 346.34 | 0.41 | 0.41 |
| 346.34 | 0.41 | 0.41 |
| 295.35 | 1.67 | 1.67 |
| 286.33 | 1.11 | 1.11 |
| 272.30 | 0.80 | 0.80 |
| 350.16 | 0.55 | 0.55 |
| 316.31 | 0.40 | 0.40 |
| 330.34 | 0.71 | 0.71 |
| 271.23 | -2.01 | -2.01 |
| 267.31 | 1.02 | 1.02 |
| 272.67 | 1.57 | 1.57 |
| 380.57 | 2.04 | 2.04 |
| 324.38 | 2.49 | 2.49 |
| 310.36 | 2.10 | 2.10 |
| 350.12 | 0.41 | 0.41 |
| 283.31 | 0.61 | 0.61 |
| 244.25 | 0.22 | 0.22 |
| 290.37 | 1.24 | 1.24 |
| 336.13 | 0.47 | 0.47 |
| 210.23 | -0.13 | -0.13 |
| 366.16 | -0.31 | -0.31 |
| 240.26 | -0.91 | -0.91 |
| 286.29 | 0.79 | 0.79 |
| 396.57 | 1.62 | 1.62 |
| 275.31 | 0.22 | 0.22 |
| 294.74 | 1.30 | 1.30 |
| 275.36 | 1.45 | 1.45 |
| 366.16 | -0.31 | -0.31 |
| 386.22 | 0.11 | 0.11 |
| 366.24 | -1.16 | -1.16 |
| 278.36 | 0.54 | 0.54 |
| 185.18 | -0.73 | -0.73 |
| 246.19 | -1.87 | -1.87 |
| 324.33 | -1.45 | -1.45 |
| 364.27 | -0.09 | -0.09 |
| 351.10 | -0.73 | -0.73 |
| 289.38 | 1.84 | 1.84 |
| 290.37 | 1.24 | 1.24 |
| 283.24 | -2.66 | -2.66 |
| 282.25 | -2.48 | -2.48 |
| 296.28 | -1.82 | -1.82 |
| 383.26 | 0.03 | 0.03 |
| 285.24 | -1.71 | -1.71 |
| 245.21 | -1.59 | -1.59 |
| 281.25 | -0.49 | -0.49 |
| 259.25 | 1.12 | 1.12 |
| 241.26 | 0.98 | 0.98 |
| 296.28 | -2.09 | -2.09 |
| 310.31 | -1.70 | -1.70 |
| 290.30 | -2.09 | -2.09 |
| 505.53 | 4.70 | 4.70 |
| 288.69 | -0.61 | -0.61 |
| 249.23 | -0.74 | -0.74 |
| 320.32 | -2.28 | -2.28 |
| 274.30 | -1.10 | -1.10 |
| 294.31 | -0.67 | -0.67 |
| 445.82 | 2.74 | 2.74 |
| 362.34 | -0.95 | -0.95 |
| 276.34 | 0.65 | 0.65 |
| 295.77 | 1.72 | 1.72 |
| 277.33 | 0.04 | 0.04 |
| 328.32 | -0.42 | -0.42 |
| 266.25 | -1.45 | -1.45 |
| 270.29 | -0.87 | -0.87 |
| 443.80 | 2.90 | 2.90 |
| 283.24 | -1.01 | -1.01 |
| 307.10 | -1.06 | -1.06 |
| 296.76 | 1.11 | 1.11 |
| 247.30 | 0.82 | 0.82 |
| 350.16 | 0.55 | 0.55 |
| 224.26 | -0.05 | -0.05 |
| 269.69 | 1.01 | 1.01 |
| 268.23 | -2.87 | -2.87 |
| 252.23 | -1.84 | -1.84 |
| 425.18 | -1.77 | -1.77 |
| 333.14 | 0.44 | 0.44 |
| 228.25 | 0.63 | 0.63 |
| 319.11 | 0.39 | 0.39 |
| 361.14 | 0.96 | 0.96 |
| 338.54 | 1.47 | 1.47 |
| 380.14 | -0.42 | -0.42 |
| 376.37 | -0.56 | -0.56 |
| 247.30 | 0.82 | 0.82 |
| 233.28 | 0.74 | 0.74 |
| 248.29 | 0.21 | 0.21 |
| 417.45 | 0.32 | 0.32 |
| 342.15 | -0.06 | -0.06 |
| 297.70 | -0.22 | -0.22 |
| 398.37 | 0.03 | 0.03 |
| 258.23 | -2.33 | -2.33 |
| 262.32 | 0.71 | 0.71 |
| 281.75 | 1.79 | 1.79 |
| 263.31 | 0.11 | 0.11 |
| 326.31 | 1.03 | 1.03 |
| 389.15 | -0.02 | -0.02 |
| 342.15 | -0.06 | -0.06 |
| 285.28 | -1.25 | -1.25 |
| 303.37 | 0.95 | 0.95 |
| 305.38 | 1.20 | 1.20 |
| 263.30 | -0.04 | -0.04 |
| 303.28 | 0.35 | 0.35 |
| 278.20 | 1.42 | 1.42 |
| 249.23 | -0.74 | -0.74 |
| 360.29 | -0.97 | -0.97 |
| 310.36 | -0.70 | -0.70 |
| 254.25 | -1.29 | -1.29 |
| 277.33 | 0.36 | 0.36 |
| 276.34 | 1.16 | 1.16 |
| 248.29 | 0.53 | 0.53 |
| 291.36 | 0.95 | 0.95 |
| 249.27 | -0.08 | -0.08 |
| 295.30 | -1.72 | -1.72 |
| 276.30 | -0.06 | -0.06 |
| 290.37 | 1.55 | 1.55 |
| 322.28 | 2.05 | 2.05 |
| 309.80 | 2.42 | 2.42 |
| 291.36 | 0.75 | 0.75 |
| 310.79 | 1.82 | 1.82 |
| 277.33 | 0.56 | 0.56 |
| 249.27 | -0.08 | -0.08 |
| 450.47 | -0.37 | -0.37 |
| 308.30 | -0.95 | -0.95 |
| 292.30 | -0.68 | -0.68 |
| 271.32 | 1.09 | 1.09 |
| 310.35 | 0.38 | 0.38 |
| 332.40 | -0.34 | -0.34 |
| 428.44 | 1.32 | 1.32 |
| 406.44 | 0.79 | 0.79 |
| 392.41 | 0.48 | 0.48 |
| 308.33 | -0.43 | -0.43 |
| 296.28 | -2.09 | -2.09 |
| 280.28 | -1.06 | -1.06 |
| 278.26 | -1.29 | -1.29 |
| 268.23 | -1.85 | -1.85 |
| 322.36 | 0.11 | 0.11 |
| 308.33 | -0.28 | -0.28 |
| 292.34 | 0.46 | 0.46 |
| 264.29 | 0.23 | 0.23 |
| 278.32 | -0.25 | -0.25 |
| 345.24 | 1.73 | 1.73 |
| 335.11 | -0.02 | -0.02 |
| 240.22 | -1.75 | -1.75 |
| 312.37 | 0.30 | 0.30 |
| 268.28 | -1.27 | -1.27 |
| 304.10 | -0.57 | -0.57 |
| 259.65 | -0.68 | -0.68 |
| 244.20 | -2.12 | -2.12 |
| 248.29 | 0.94 | 0.94 |
| 290.37 | 1.55 | 1.55 |
| 241.21 | -1.63 | -1.63 |
| 291.36 | 1.06 | 1.06 |
| 263.30 | 0.84 | 0.84 |
| 296.33 | 1.80 | 1.80 |
| 234.26 | 0.87 | 0.87 |
| 264.29 | -0.33 | -0.33 |
| 500.92 | -0.97 | -0.97 |
| 288.69 | -0.61 | -0.61 |
| 280.24 | -1.51 | -1.51 |