Basic Information
ID: ALA921041
Type: Binding
Description: Inhibition of human autotaxin expressed in MDA-MB-435 cells assessed as fluorescent lysophosphatidyl choline analog hydrolysis at 10 uM
Organism: Homo sapiens
Cell type: MDA-MB-435
Activity Charts
Bioactivity
Activity Types for Assay ALA921041
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 285.26 | 0.70 | 0.70 |
| 420.81 | 4.09 | 4.09 |
| 532.99 | 8.17 | 8.17 |
| 439.52 | 1.33 | 1.33 |
| 813.74 | 8.33 | 8.33 |
| 508.63 | 0.80 | 0.80 |
| 414.51 | 2.04 | 2.04 |
| 499.39 | 2.14 | 2.14 |
| 580.69 | 10.26 | 10.26 |
| 492.44 | 1.24 | 1.24 |
| 572.58 | 6.83 | 6.83 |
| 507.40 | 3.34 | 3.34 |
| 320.41 | 2.87 | 2.87 |
| 292.40 | 3.09 | 3.09 |
| 305.40 | 2.65 | 2.65 |
| 524.58 | 6.94 | 6.94 |
| 672.69 | 6.43 | 6.43 |
| 491.59 | 9.44 | 9.44 |
| 528.56 | 5.75 | 5.75 |
| 506.54 | -0.39 | -0.39 |
| 437.50 | 1.90 | 1.90 |
| 563.61 | 3.66 | 3.66 |
| 490.48 | 5.85 | 5.85 |
| 385.25 | 3.20 | 3.20 |
| 520.49 | 2.02 | 2.02 |
| 506.14 | 6.93 | 6.93 |
| 507.45 | 4.91 | 4.91 |
| 556.53 | 4.92 | 4.92 |
| 434.36 | 2.72 | 2.72 |
| 396.36 | 2.34 | 2.34 |
| 414.46 | 1.00 | 1.00 |
| 443.48 | 2.69 | 2.69 |
| 303.23 | 1.23 | 1.23 |
| 502.48 | 5.52 | 5.52 |
| 632.68 | 7.96 | 7.96 |
| 802.11 | 5.36 | 5.36 |
| 400.48 | 1.90 | 1.90 |
| 354.48 | 4.87 | 4.87 |
| 588.53 | 4.37 | 4.37 |
| 560.47 | 3.92 | 3.92 |
| 318.49 | 3.87 | 3.87 |
| 498.57 | 2.05 | 2.05 |
| 514.58 | 3.39 | 3.39 |
| 448.52 | 2.13 | 2.13 |
| 281.27 | 2.18 | 2.18 |
| 301.38 | 2.56 | 2.56 |
| 630.25 | 6.04 | 6.04 |
| 508.44 | 5.12 | 5.12 |
| 588.53 | 4.53 | 4.53 |
| 588.53 | 4.37 | 4.37 |
| 483.50 | 2.84 | 2.84 |
| 476.49 | 2.30 | 2.30 |
| 292.38 | 2.73 | 2.73 |
| 543.54 | 5.78 | 5.78 |
| 588.53 | 4.09 | 4.09 |
| 586.56 | 4.44 | 4.44 |
| 427.44 | 3.66 | 3.66 |
| 496.57 | 4.21 | 4.21 |
| 282.32 | 0.58 | 0.58 |
| 524.57 | 3.46 | 3.46 |
| 269.21 | 1.78 | 1.78 |
| 408.44 | 2.22 | 2.22 |
| 472.49 | 3.21 | 3.21 |
| 447.50 | 2.04 | 2.04 |
| 402.36 | 3.14 | 3.14 |
| 276.41 | 3.31 | 3.31 |
| 383.41 | 5.97 | 5.97 |
| 457.35 | 2.08 | 2.08 |
| 513.51 | 6.36 | 6.36 |
| 560.56 | 5.32 | 5.32 |
| 588.53 | 3.91 | 3.91 |
| 280.37 | 3.22 | 3.22 |
| 424.41 | 2.98 | 2.98 |
| 310.31 | 2.52 | 2.52 |
| 410.38 | 2.73 | 2.73 |
| 692.69 | 4.11 | 4.11 |
| 613.68 | 9.43 | 9.43 |
| 624.65 | 7.85 | 7.85 |
| 504.47 | 2.06 | 2.06 |
| 469.41 | 2.75 | 2.75 |
| 479.44 | 4.91 | 4.91 |
| 588.53 | 4.53 | 4.53 |
| 502.49 | 3.93 | 3.93 |
| 531.61 | 6.96 | 6.96 |
| 610.49 | 2.53 | 2.53 |
| 436.42 | 3.26 | 3.26 |
| 394.38 | 2.41 | 2.41 |
| 650.60 | 2.51 | 2.51 |
| 500.51 | 4.51 | 4.51 |
| 676.55 | 3.77 | 3.77 |
| 416.48 | 3.15 | 3.15 |
| 289.29 | 0.84 | 0.84 |
| 295.30 | 3.68 | 3.68 |
| 437.54 | 2.57 | 2.57 |
| 294.45 | 3.04 | 3.04 |
| 560.47 | 3.92 | 3.92 |
| 436.54 | 3.62 | 3.62 |
| 532.51 | 4.55 | 4.55 |
| 648.49 | 3.31 | 3.31 |
| 403.50 | 2.42 | 2.42 |
| 558.62 | 3.94 | 3.94 |
| 579.90 | 7.04 | 7.04 |
| 560.48 | 1.59 | 1.59 |
| 532.51 | 4.54 | 4.54 |
| 462.53 | 3.54 | 3.54 |
| 407.52 | 2.48 | 2.48 |
| 461.53 | 2.35 | 2.35 |
| 552.12 | 8.09 | 8.09 |
| 505.48 | 5.41 | 5.41 |
| 557.56 | 2.26 | 2.26 |
| 756.85 | 8.77 | 8.77 |
| 423.52 | 2.09 | 2.09 |
| 412.35 | 1.58 | 1.58 |
| 305.29 | 1.63 | 1.63 |
| 396.40 | 1.89 | 1.89 |
| 672.79 | 12.05 | 12.05 |
| 500.51 | 5.14 | 5.14 |
| 556.53 | 4.92 | 4.92 |
| 486.87 | 4.95 | 4.95 |
| 317.35 | 5.26 | 5.26 |
| 349.30 | 0.52 | 0.52 |
| 432.46 | 2.29 | 2.29 |
| 472.59 | 3.04 | 3.04 |
| 371.35 | 4.60 | 4.60 |
| 307.42 | 1.99 | 1.99 |
| 400.39 | 3.75 | 3.75 |
| 386.36 | 3.44 | 3.44 |
| 547.60 | 2.31 | 2.31 |
| 400.39 | 3.37 | 3.37 |
| 290.43 | 3.09 | 3.09 |
| 434.84 | 4.02 | 4.02 |
| 412.36 | 3.35 | 3.35 |
| 438.39 | 2.11 | 2.11 |
| 429.38 | 3.23 | 3.23 |
| 393.38 | 2.89 | 2.89 |
| 410.38 | 2.12 | 2.12 |
| 404.33 | 3.89 | 3.89 |
| 401.38 | 2.83 | 2.83 |
| 416.39 | 3.45 | 3.45 |
| 392.41 | 3.57 | 3.57 |
| 417.53 | 2.62 | 2.62 |
| 490.48 | 5.85 | 5.85 |
| 411.37 | 3.90 | 3.90 |
| 570.63 | 2.97 | 2.97 |
| 445.39 | 2.53 | 2.53 |
| 431.97 | 1.42 | 1.42 |