Basic Information
ID: ALA924858
Type: Binding
Description: Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of [3H]cortisone to [3H]cortisol by SPA assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA924858
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.38 | 2.52 | 2.52 |
| 396.39 | 2.48 | 2.48 |
| 401.41 | 2.62 | 2.62 |
| 439.38 | 3.63 | 3.63 |
| 376.50 | 3.63 | 3.63 |
| 405.83 | 3.26 | 3.26 |
| 389.37 | 2.75 | 2.75 |
| 413.47 | 3.73 | 3.73 |
| 427.49 | 3.91 | 3.91 |
| 413.47 | 3.56 | 3.56 |
| 385.41 | 2.92 | 2.92 |
| 399.44 | 3.17 | 3.17 |
| 321.35 | 3.42 | 3.42 |
| 385.41 | 2.75 | 2.75 |
| 335.33 | 3.06 | 3.06 |
| 372.53 | 3.80 | 3.80 |
| 371.38 | 2.61 | 2.61 |
| 392.95 | 4.15 | 4.15 |
| 403.50 | 3.40 | 3.40 |
| 417.53 | 3.79 | 3.79 |
| 426.50 | 4.51 | 4.51 |
| 403.50 | 3.40 | 3.40 |
| 376.50 | 3.63 | 3.63 |
| 417.53 | 3.79 | 3.79 |
| 441.52 | 4.30 | 4.30 |
| 441.52 | 4.30 | 4.30 |
| 392.95 | 4.15 | 4.15 |
| 372.53 | 3.80 | 3.80 |
| 455.55 | 4.69 | 4.69 |
| 351.86 | 2.55 | 2.55 |
| 317.41 | 1.90 | 1.90 |
| 331.44 | 2.21 | 2.21 |
| 440.27 | 3.92 | 3.92 |
| 439.38 | 3.63 | 3.63 |
| 455.55 | 4.69 | 4.69 |
| 441.52 | 4.30 | 4.30 |
| 421.44 | 3.76 | 3.76 |
| 405.83 | 3.26 | 3.26 |
| 441.52 | 4.30 | 4.30 |
| 421.44 | 3.76 | 3.76 |
| 447.48 | 4.28 | 4.28 |