Basic Information
ID: ALA924950
Type: Binding
Description: Inhibition of MMP2
Format: BAO_0000357
Target: Matrix metalloproteinase-2(ALA333)
Document: ALA1140610
Inhibition of MMP2: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA924950
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.42 | 0.16 | 0.16 |
| 385.44 | 0.55 | 0.55 |
| 343.36 | -0.62 | -0.62 |
| 419.46 | 0.95 | 0.95 |
| 411.48 | 1.08 | 1.08 |
| 349.43 | 1.02 | 1.02 |
| 377.49 | 1.80 | 1.80 |
| 395.39 | 1.30 | 1.30 |
| 507.29 | 2.66 | 2.66 |
| 455.32 | 1.99 | 1.99 |
| 362.47 | 2.52 | 2.52 |
| 390.52 | 3.30 | 3.30 |
| 377.49 | 1.94 | 1.94 |
| 446.63 | 4.86 | 4.86 |
| 461.65 | 4.28 | 4.28 |
| 517.76 | 5.84 | 5.84 |
| 376.50 | 2.91 | 2.91 |
| 433.59 | 3.50 | 3.50 |
| 489.70 | 5.06 | 5.06 |
| 411.50 | 1.99 | 1.99 |
| 405.54 | 2.72 | 2.72 |
| 391.51 | 2.33 | 2.33 |
| 419.57 | 3.11 | 3.11 |
| 418.58 | 4.08 | 4.08 |
| 502.74 | 6.42 | 6.42 |
| 488.71 | 6.03 | 6.03 |
| 474.69 | 5.64 | 5.64 |
| 404.55 | 3.69 | 3.69 |
| 469.34 | 2.38 | 2.38 |
| 521.31 | 3.05 | 3.05 |
| 409.42 | 1.69 | 1.69 |
| 350.40 | 1.39 | 1.39 |
| 260.27 | -0.52 | -0.52 |
| 392.48 | 2.42 | 2.42 |
| 364.42 | 1.78 | 1.78 |
| 431.60 | 1.99 | 1.99 |
| 532.71 | 3.32 | 3.32 |
| 377.51 | 0.67 | 0.67 |
| 337.44 | -0.25 | -0.25 |
| 469.60 | 2.11 | 2.11 |
| 391.53 | 1.06 | 1.06 |
| 495.64 | 2.65 | 2.65 |
| 417.57 | 1.60 | 1.60 |
| 558.75 | 3.86 | 3.86 |
| 431.60 | 1.99 | 1.99 |
| 429.58 | 1.74 | 1.74 |
| 457.52 | 2.10 | 2.10 |
| 457.64 | 2.52 | 2.52 |
| 515.68 | 3.79 | 3.79 |
| 403.55 | 1.21 | 1.21 |
| 497.61 | 1.49 | 1.49 |
| 405.52 | 0.05 | 0.05 |
| 432.59 | 1.06 | 1.06 |
| 500.06 | 3.29 | 3.29 |
| 431.60 | 1.99 | 1.99 |
| 537.70 | 4.22 | 4.22 |
| 541.65 | 2.80 | 2.80 |
| 525.65 | 3.18 | 3.18 |
| 516.04 | 3.44 | 3.44 |
| 571.67 | 2.81 | 2.81 |
| 541.65 | 2.80 | 2.80 |
| 617.59 | 4.82 | 4.82 |
| 686.44 | 6.45 | 6.45 |
| 588.70 | 4.94 | 4.94 |
| 618.73 | 4.95 | 4.95 |
| 542.68 | 5.23 | 5.23 |
| 395.39 | 1.30 | 1.30 |
| 455.32 | 1.99 | 1.99 |
| 376.30 | 1.58 | 1.58 |
| 466.43 | 3.49 | 3.49 |
| 518.40 | 4.16 | 4.16 |
| 316.38 | 0.89 | 0.89 |
| 398.87 | 2.43 | 2.43 |
| 458.79 | 3.12 | 3.12 |
| 302.35 | 0.50 | 0.50 |
| 362.28 | 1.19 | 1.19 |
| 372.16 | 0.84 | 0.84 |
| 386.19 | 1.23 | 1.23 |
| 334.22 | 0.55 | 0.55 |
| 507.29 | 2.66 | 2.66 |
| 406.50 | 2.81 | 2.81 |
| 462.29 | 2.75 | 2.75 |
| 410.32 | 2.08 | 2.08 |
| 320.19 | 0.17 | 0.17 |
| 504.37 | 3.77 | 3.77 |
| 452.40 | 3.10 | 3.10 |
| 428.27 | 2.25 | 2.25 |
| 414.25 | 1.86 | 1.86 |
| 510.76 | 3.79 | 3.79 |
| 409.42 | 1.69 | 1.69 |
| 469.34 | 2.38 | 2.38 |
| 521.31 | 3.05 | 3.05 |
| 476.32 | 3.14 | 3.14 |
| 274.30 | -0.13 | -0.13 |
| 424.35 | 2.47 | 2.47 |
| 543.71 | 5.13 | 5.13 |
| 424.54 | 4.27 | 4.27 |
| 362.47 | 2.38 | 2.38 |
| 497.64 | 3.56 | 3.56 |
| 497.64 | 3.56 | 3.56 |
| 481.64 | 4.10 | 4.10 |
| 440.54 | 3.09 | 3.09 |
| 439.56 | 3.69 | 3.69 |
| 445.60 | 3.50 | 3.50 |
| 481.64 | 4.32 | 4.32 |
| 467.61 | 3.93 | 3.93 |
| 481.64 | 4.32 | 4.32 |
| 419.57 | 2.97 | 2.97 |
| 431.58 | 3.11 | 3.11 |
| 452.60 | 4.51 | 4.51 |
| 466.62 | 4.68 | 4.68 |
| 466.62 | 4.90 | 4.90 |
| 452.60 | 4.51 | 4.51 |
| 404.55 | 3.55 | 3.55 |
| 482.62 | 4.14 | 4.14 |
| 482.62 | 4.14 | 4.14 |
| 466.62 | 4.90 | 4.90 |
| 430.59 | 4.08 | 4.08 |
| 529.68 | 4.96 | 4.96 |
| 467.61 | 3.93 | 3.93 |
| 514.67 | 5.54 | 5.54 |
| 425.53 | 3.66 | 3.66 |
| 528.69 | 5.71 | 5.71 |
| 416.56 | 3.69 | 3.69 |
| 387.41 | -0.60 | -0.60 |
| 632.75 | 4.95 | 4.95 |