Basic Information
ID: ALA926594
Type: Binding
Description: Inhibition of human TTR amyloidogenesis assessed as fibril formation at 7.2 uM after 72 hrs by acid-mediated aggregation assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA926594
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 195.22 | 3.49 | 3.49 |
| 213.21 | 3.63 | 3.63 |
| 229.67 | 4.15 | 4.15 |
| 274.12 | 4.26 | 4.26 |
| 321.12 | 4.10 | 4.10 |
| 209.25 | 3.80 | 3.80 |
| 263.22 | 4.51 | 4.51 |
| 211.22 | 3.20 | 3.20 |
| 225.25 | 3.50 | 3.50 |
| 231.20 | 3.77 | 3.77 |
| 264.11 | 4.80 | 4.80 |
| 353.01 | 5.02 | 5.02 |
| 223.28 | 4.11 | 4.11 |
| 331.21 | 5.53 | 5.53 |
| 227.22 | 2.91 | 2.91 |
| 255.27 | 3.51 | 3.51 |
| 211.22 | 3.20 | 3.20 |
| 229.21 | 3.34 | 3.34 |
| 245.66 | 3.85 | 3.85 |
| 290.12 | 3.96 | 3.96 |
| 337.12 | 3.81 | 3.81 |
| 225.25 | 3.51 | 3.51 |
| 279.22 | 4.22 | 4.22 |
| 227.22 | 2.91 | 2.91 |
| 247.20 | 3.48 | 3.48 |
| 280.11 | 4.51 | 4.51 |
| 369.01 | 4.73 | 4.73 |
| 463.01 | 4.41 | 4.41 |
| 239.27 | 3.82 | 3.82 |
| 225.25 | 3.50 | 3.50 |
| 243.24 | 3.64 | 3.64 |
| 259.69 | 4.16 | 4.16 |
| 304.14 | 4.27 | 4.27 |
| 351.14 | 4.11 | 4.11 |
| 239.27 | 3.81 | 3.81 |
| 293.24 | 4.52 | 4.52 |
| 255.27 | 3.51 | 3.51 |
| 261.23 | 3.78 | 3.78 |
| 294.14 | 4.81 | 4.81 |
| 383.04 | 5.03 | 5.03 |
| 477.04 | 4.71 | 4.71 |
| 253.30 | 4.12 | 4.12 |