Basic Information
ID: ALA926774
Type: ADME
Description: Prodrug activation in Wistar rat liver microsome assessed as formation of adefovir at 250 uM after 5 mins
Format: BAO_0000251
Organism: Rattus norvegicus
Strain: Wistar
Tissue: Liver
Subcellular Fraction: Microsome
Target: Liver microsomes(ALA613694)
Document: ALA1140725
Prodrug activation in Wistar rat liver microsome assessed as formation of adefovir at 250 uM after 5 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA926774
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.35 | 2.75 | 2.75 |
| 417.41 | 3.37 | 3.37 |
| 445.46 | 4.05 | 4.05 |
| 407.34 | 2.89 | 2.89 |
| 423.80 | 3.41 | 3.41 |
| 468.25 | 3.52 | 3.52 |
| 407.34 | 2.89 | 2.89 |
| 423.80 | 3.41 | 3.41 |
| 468.25 | 3.52 | 3.52 |
| 425.33 | 3.03 | 3.03 |
| 425.33 | 3.03 | 3.03 |
| 425.33 | 3.03 | 3.03 |
| 425.33 | 3.03 | 3.03 |
| 425.33 | 3.03 | 3.03 |
| 458.24 | 4.06 | 4.06 |
| 458.24 | 4.06 | 4.06 |
| 458.24 | 4.06 | 4.06 |
| 458.24 | 4.06 | 4.06 |
| 458.24 | 4.06 | 4.06 |
| 498.27 | 3.53 | 3.53 |
| 498.27 | 3.53 | 3.53 |
| 498.27 | 3.53 | 3.53 |
| 390.34 | 2.15 | 2.15 |
| 390.34 | 2.15 | 2.15 |
| 379.31 | 2.35 | 2.35 |
| 395.38 | 2.82 | 2.82 |
| 423.80 | 3.41 | 3.41 |
| 423.80 | 3.41 | 3.41 |