Basic Information
ID: ALA927683
Type: Binding
Description: Inhibition of HER2 sheddase in BT474 cells by extracellular domain shedding assay
Cell type: BT-474
Activity Charts
Bioactivity
Activity Types for Assay ALA927683
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.44 | 0.60 | 0.60 |
| 355.44 | 1.57 | 1.57 |
| 357.45 | 1.66 | 1.66 |
| 341.41 | 1.18 | 1.18 |
| 369.46 | 1.87 | 1.87 |
| 383.49 | 2.13 | 2.13 |
| 385.46 | 1.57 | 1.57 |
| 397.52 | 2.69 | 2.69 |
| 395.50 | 2.44 | 2.44 |
| 383.49 | 2.18 | 2.18 |
| 422.53 | 2.56 | 2.56 |
| 408.50 | 2.05 | 2.05 |
| 391.42 | 1.84 | 1.84 |
| 424.33 | 2.87 | 2.87 |
| 372.47 | 0.91 | 0.91 |
| 397.48 | 0.78 | 0.78 |
| 392.89 | 1.25 | 1.25 |
| 400.52 | 1.72 | 1.72 |
| 371.48 | 1.96 | 1.96 |
| 399.54 | 2.78 | 2.78 |
| 413.47 | 2.26 | 2.26 |
| 455.56 | 3.28 | 3.28 |
| 489.57 | 3.83 | 3.83 |
| 397.48 | 2.04 | 2.04 |
| 433.53 | 1.45 | 1.45 |
| 415.49 | 2.14 | 2.14 |
| 486.57 | 1.63 | 1.63 |
| 436.53 | 0.27 | 0.27 |
| 343.43 | 1.27 | 1.27 |
| 401.46 | 1.75 | 1.75 |
| 399.45 | 1.65 | 1.65 |