Basic Information
ID: ALA927854
Type: Binding
Description: Inhibition of HER2 sheddase in human BT474 cells
Format: BAO_0000219
Organism: Homo sapiens
Cell type: BT-474
Target: ADAM10(ALA5028)
Document: ALA1140810
Inhibition of HER2 sheddase in human BT474 cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA927854
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 479.56 | 1.23 | 1.23 |
| 481.57 | 1.32 | 1.32 |
| 496.59 | 0.65 | 0.65 |
| 493.58 | 1.62 | 1.62 |
| 495.60 | 1.71 | 1.71 |
| 513.59 | 1.85 | 1.85 |
| 520.61 | 1.58 | 1.58 |
| 509.63 | 2.02 | 2.02 |
| 563.60 | 2.73 | 2.73 |
| 527.62 | 2.16 | 2.16 |
| 580.70 | 1.72 | 1.72 |
| 534.64 | 1.89 | 1.89 |
| 520.61 | 1.58 | 1.58 |
| 548.66 | 2.20 | 2.20 |
| 523.65 | 2.33 | 2.33 |
| 510.61 | 0.96 | 0.96 |
| 507.61 | 1.93 | 1.93 |
| 535.62 | 0.83 | 0.83 |
| 532.62 | 1.80 | 1.80 |
| 523.65 | 2.41 | 2.41 |
| 537.68 | 2.65 | 2.65 |
| 523.65 | 2.14 | 2.14 |
| 508.64 | 1.59 | 1.59 |
| 522.67 | 1.98 | 1.98 |
| 522.67 | 1.98 | 1.98 |
| 547.68 | 1.85 | 1.85 |
| 547.68 | 1.85 | 1.85 |
| 533.65 | 1.46 | 1.46 |
| 545.66 | 1.76 | 1.76 |
| 545.66 | 1.76 | 1.76 |